Lipid Feeding and Serum Esterases

  • Hein A. Van Lith
  • Bert F. M. Van Zutphen
  • Anton C. Beynen
Part of the NATO ASI Series book series (NSSA, volume 266)


A brief review is given of the effects of the amount and type of dietary lipid on serum esterase activities in rabbits and selected rodent species. The feeding of a cholesterol-rich diet causes an increased activity of serum total esterase in rats, rabbits and mice. Cholesterol loading of rats, but not rabbits, lowers serum butyrylcholinesterase activity. The activity or level of a fast anodal serum esterase zone in rats (ES-1) and mice (ES-2) is raised after cholesterol feeding. The concentration and type of dietary fat influence ES-1 and total esterase activity in the serum of rats. Increased fat intakes markedly elevate serum ES-1 activity and slightly increase serum total esterase activity. The magnitude of this effect depends on the type of fat. In contrast to rats, the activity of an anodal fast moving serum esterase zone is decreased in gerbils after feeding a high-fat diet. Serum butyrylcholinesterase activities of rats and rabbits are slightly increased with increasing fat intakes. In gerbils, such an effect does not occur. Dietary fish oil when compared with either coconut fat, corn oil or olive oil produces increased activities of serum butyrylcholinesterase in rats.


Esterase Activity Dietary Cholesterol Zealand White Rabbit Cholesterol Feeding Arylesterase Activity 
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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Hein A. Van Lith
    • 1
  • Bert F. M. Van Zutphen
    • 1
  • Anton C. Beynen
    • 1
  1. 1.Department of Laboratory Animal Science, Faculty of Veterinary MedicineUtrecht UniversityUtrechtThe Netherlands

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