Lipoprotein Lipase and Lysosomal Acid Lipase: Two Key Enzymes of Lipid Metabolism

  • Detlev Ameis
  • Heiner Greten
Part of the NATO ASI Series book series (NSSA, volume 266)


Lipases play a central role in the metabolism of triglyceride-rich lipoproteins in plasma and have therefore been extensively studied at the biochemical and molecular level. Primary structures from various species have been established for lipoprotein lipase (LPL), hepatic lipase (HL), pancreatic lipase (PL), and lysosomal acid lipase (LAL). Comparison of cDNA and genomic structures revealed a gene family of neutral lipases consisting of LPL, HL, and PL. Another gene family of acid lipases comprised LAL, gastric lipase, and lingual lipase.


Lipoprotein Lipase Hepatic Lipase Cholesteryl Ester Hydrolase Lysosomal Acid Lipase Deficiency Lipoprotein Lipase Gene 
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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Detlev Ameis
    • 1
  • Heiner Greten
    • 1
  1. 1.Medizinische Kern- und PoliklinikUniversitäts-Krankenhaus EppendorfHamburgGermany

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