Haemorrhagic Septicaemia (Pasteurella Multocida Serotype B:2 and E:2 Infection) in Cattle and Buffaloes

  • M. C. L. de Alwis


The genus Pasteurella consists of a large number of species with a worldwide distribution and causing a wide range of diseases in animals and man. Diseases of economic importance to agricultural animals is associated with two species Pasteurella multocida and Pasteurella haemolvtica.


Live Vaccine Buffalo Calf Snow Leopard Serological Type Pasteurella Multocida 
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  1. Abenayake, P., Wijewardana, T.G., and Thalagoda, S.A., 1993, Sulphonamide resistance in Pasteurella multocida (Serotype 6:B) in Sri Lanka. Presentation at the 46th Annual Sessions of the Sri Lanka Veterinary Association December 1993.Google Scholar
  2. Bain, R.V.S., 1954, Studies on haemorrhagic septicaemia in cattle. I naturally acquired immunity in Siamese buffaloes, Br.Vet.J. 110: 481.Google Scholar
  3. Bain, R.V.S., 1955, A preliminary examination of antigens of Pasteurella multocida type 1, Br.Vet.J. 111: 492.Google Scholar
  4. Bain. R.V.S., De Alwis, M.C.L., Carter. G.R. and Gupta, B.K., 1982, Haemorrhagic Septicaemia, Animal Production and Health Paper No. 33, FAO, Rome.Google Scholar
  5. Bhatty, M.A., 1973, A preliminary comparison of sodium alginate and oil adjuvant haemorrhagic septicaemia vaccines in cattle. Bull. epizoot. Dis. Afi•. 21: 171.Google Scholar
  6. Bollinger 1878. Cited by Hudson, J.R., ‘Infectious Diseases of Animals: Diseases due to Bacteria, Vol.2. Pasteurellosis, A.W. Stableforth and I.A. Galloway. P. 421, Butterworth Scientific Publications, London.Google Scholar
  7. Brogden,K.A. and Packer, R.A., 1979, Comparison of Pasteurella multocida serotyping systems, Am. J. Vet.Res. Res. 40: 1332.Google Scholar
  8. Carrigan, M.J., Dawkins. H.J.S. Cockram, F.A. and Hausen, A.T. 1991, Pasteurelta multocida septicaemia in fallow deer (Dama dama). Aust. Vet. J. 68: 201.Google Scholar
  9. Carter, G.R., 1957, Studies on Pasteurella multocida. iiI A serological survey of bovine and porcine strains from various parts of the world. Scholar
  10. Carter, G.R., 1959, Studies on Pasteurella multocida IV. Serological types from species other than cattle and swine, 21: 173.Google Scholar
  11. Carter, G.R., 1961, A new serological type of Pasteurella nndtocida, Vet.Rec. 73: 1052.Google Scholar
  12. Carter, G.R., 1982, Whatever happened to haemorrhagic septicaemia? med. Ass. 180: 1176.Google Scholar
  13. Carter, G.R., and Chengappa, M.M., 1980, Hyaluronidase production by type B Pasteurella multocida from cases of haemorrhagic septicaemia,./. clip. Microbial. 11: 94Google Scholar
  14. Carter, G.R. and Rappay. D.E., 1962, Formalinised erythrocytes in the haemagglutination test for typing Pasteurella multocida, Br. Vet.I.118:289.Google Scholar
  15. Chandrasekeran, S., Muniandy, N., Kennet,i. and Mukkur, T.K.S. 1991. Protection, antibody response and isotype specificity in buffaloes immunised with conventional haemorrhagic septicaemia vaccines. Proc. FAO/APHCA workshop on haemorrhagic septicaemia, Feb. 1991, Kandy, Sri Lanka.Google Scholar
  16. Chandrasekeran, S. and Yeap, P.C., 1978. Safety and potency testing of haemorrhagic septicaemia oil adjuvant vaccine by mouse protection test, Kajian Veterinar, 10: 28.Google Scholar
  17. Chandrasekeran, S. Yeap.P.C. and Saad, R., 1987, Effect of storage conditions on the stability and potency of haemorrhagic septicaemia oil adjuvant vaccine. Kajian Veterinar, 19: 71.Google Scholar
  18. Chaudhuri, S., Mukherjee, S.K., Chatterjee. A. and Ganguli. J.L., 1992, isolation of Pasteurella multocida serotype F:3,4 from a stillborn snow leopard. Vet. Rec. 130: 36.Google Scholar
  19. Dassanayake, L., 1957. The haemorrhagic septicaemic outbreak of 1955–56, Cey. Vet.J. 5: 56.Google Scholar
  20. Dawkins. H.J.S., Johnson, R.B. Spencer, T.L. and Patten, B.E., 1990, Rapid identification of Pasteurella multocida organisms responsible for haemorrhagic septicaemia using an enzyme linked immunosorbent assay (ELISA), Res. Vet. Sci. 49: 261.Google Scholar
  21. De Alwis, M.C.L., 1981, Mortality among cattle and buffaloes in Sri Lanka due to haemorrhagic septicaemia, Trap. anim. Nth Prod. 13: 195.CrossRefGoogle Scholar
  22. De Alwis, M.C.L., 1982a. Pasteurella multocida serotype 6:B from an elephant. Sri Lanka Vet.,1.30:28.Google Scholar
  23. De Alwis, M.C.L., 1982b, The immune response of buffalo calves exposed to natural infection with haemorrhagic septicaemia. Trop. anim. hlth Prod. 14: 29.CrossRefGoogle Scholar
  24. De Alwis, M.C.L, 1984, Haemorrhagic septicaemia in cattle and buffaloes. Rev. Sci. Tech. Off. Int. Epic. 3: 707.Google Scholar
  25. De Alwis, M.C.L., 1987, Serological classification of Pasteurella multocida, Vet. Rec. 121: 44.PubMedCrossRefGoogle Scholar
  26. De Alwis, M.C.L. and Carter, G.R., 1980. Preliminary field trials with a streptomycin dependent live vaccine against haemorrhagic septicaemia. Vet. Rec. 106: 435.PubMedCrossRefGoogle Scholar
  27. De Alwis, M.C.L., Carter, G.R. and Chengappa. M.M., 1980, Production and charecterisation of streptomycin dependent mutants of Pasteurella multocida from bovine haemorrhagic septicaemia, Can.J. comp. Med. 44: 418.PubMedGoogle Scholar
  28. De Alwis, M.C.L., Gunatilcke, A.A.P. and Wickramasinghe, W.A.T. 1978. Duration of immunity to haemorrhagic septicaemia in cattle following immunisation with alum preciptated and oil adjuvant vaccines, Ceylon vet. J. J. 26: 35.Google Scholar
  29. De Alwis, M.C.L., Jayasekera. M.U. and Balasunderam. P., 1975, Pneumonic pasteurellosis in buffalo calves associated with Pasteurella multocida serotype 6:B, ceylon vet. J. 23: 58.Google Scholar
  30. De Alwis, M.C.L., Kodituwakku, A.O. and Kodituwakku,S., 1976, Haemorrhagic septicaemia: an analysis of two outbreaks of disease among buffaloes, Ceylon vet. J. 24: 18.Google Scholar
  31. De. Alwis, M.C.L., Sumanadasa. M.A., 1982, Naturally acquired immunity to haemorrhagic septicaemia among cattle and buffaloes in Sri Lanka. Trop. anim. hlth Prod. 14: 27.CrossRefGoogle Scholar
  32. De Alwis, M.C.L. and Thambithurai, V. 1965. A case of haemorrhagic septicaemia in a wild elephant in Sri Lanka, Ceylon vet. J. 13: 17.Google Scholar
  33. De Alwis, M.C.L. and Vipulasiri, A.A., 1980. Anepizootiological study of haemorrhagic septicaemia in Sri Lanka, Ceylon vet. J. 28: 24.Google Scholar
  34. De Alwis, M.C.L., Wijewardana, T.G., Gomis, A.I.U. and Vipulasiri, A.A.,1990, Persistence of the carrier status in haemorrhagic septicaemia (Pasteurella multocida serotype 6:B infection) in buffaloes, Trop. anim. hlth Prod.22:I85.Google Scholar
  35. De Alwis, M.C.L., Wijewardana, T.G., Sivaram, A. and Vipulasiri, A.A. 1986, The carrier and antibody status of cattle and buffaloes exposed to haemorrhagic septicaemia: investigations on survivors following natural outbreaks. Sri Lanka vet. J. 34: 33.Google Scholar
  36. De Alwis. M.C.L., Wijewardana, T.G., Athureliya, D.S. and Vipulasiri,A.A., 1986, Prevalence of haemorrhagic septicaemia carriers among cattle and goats in endemic areas of Sri Lanka, Sri Lanka vet. J. 34: 16.Google Scholar
  37. Dhanda, M.R., 1959, immunisation of cattle against haemorrhagic septicaemia with purfied capsular antigens (a preliminary communication), Indian vet. J. 36: 6.Google Scholar
  38. FAO, 1979, Proc. FAO/APHCA Workshop on Haemorrhagic Septicaemia, Dec. 1979, Colombo. Sri Lanka.Google Scholar
  39. FAO, 1991a. FAO- WHO-OIE Animal Health Yearbook 1991, FAO, Rome.Google Scholar
  40. FAO, 1991h, Proc. FAO/APHCA Workshop on haemorrhagic Septicaemia, Feb.1991., Colombo. Sri Lanka.Google Scholar
  41. Farid, A., El Ghani, M.A., Khalil, A. El Ghawas, A. and Kamel, A. 1980, Identification of serological types of Pasteurella multocida isolated from apparently healthy buffaloes. Agric. Res. Rev., 58: 107.Google Scholar
  42. Francis, B.K.T., Schels, H.F. and Carter. G.R., 1980, Type E Pasteurella multocida associated with haemorrhagic septicaemia in Zambia, Vet. Rec. 107: 135.PubMedCrossRefGoogle Scholar
  43. Gomis, A.I,U., De Alwis, M.C.L., Radhakrishnan. S.,and Thalagoda. S.A., 1989, Further studies on the stability and potency of haemorrhagic septicaemia oil adjuvant vaccine, Sri Lanka vet. J. 36: 9.Google Scholar
  44. Gupta. B.K., 1962, Studies on the carrier problem in haemorrhagic septicaemia, Thesis, Punjab University, Chandigar, India.Google Scholar
  45. Gupta. B.K., Mittal, K.R. and Jaiswal. T.N., 1979, Multi-emulsion haemorrhagic septicaemia oil adjuvant vaccine, Proc. FAO/APHCA Workshop on Haemorrhagic Septicaemia, Dec. 1979, Colombo. Sri Lanka.Google Scholar
  46. Gupta. M.L. and Sareen, R.L., 1976, Evaluation of haemorrhagic septicaemia oil adjuvant vaccine by mouse protection test, Indian vet. J. 53: 489.Google Scholar
  47. Hiramune, T. and De Alwis, M.C.L., 1982, Haemorrhagic septicaemia carrier status of cattle and buffaloes in Sri Lanka, Trop. anim. hlth Prod.14:92.Google Scholar
  48. Heddleston. K.L., Gallergher, J.E. and Rehers, P.A., 1972. Fowl Cholera: Gel diffusion precipitin test for semtyping Pasteurella multocida from avian species, Arian Dis. 16: 925.Google Scholar
  49. Horadagoda. N. and Belak, K. 1990, Demonstration of Pasteurella multocida type 6:B (B:2) in formalin fixed paraffin embedded tissues of buffaloes by the peroxidase antiperoxidase (PAP) technique, Acta vet. stand 31: 493.Google Scholar
  50. Kumaratileke, W.L.J.S. and Buvanendran, V., 1979, A survey of production charecteristics of indigenous buffaloes in Sri Lanka. Ceylon vet. J. 27: 10.Google Scholar
  51. Little, P.A., and Lyon, B.M.,1943, Demonstration of serological types within non-haemolytic pasteurellae, Res. 4: 110.Google Scholar
  52. Mohan, K., Singha, M.N., Singh, R.P. and Gupta, G.M., 1968, A study of immunity against Pasteurella multocida in buffalo calves, and their carrier status. Vet. Rec. 83: 155.PubMedCrossRefGoogle Scholar
  53. Mustafa, A.A., Ghalib, H.W. and Shigidi, M,T., 1978, Carrier rate of Pasteurella multocida in cattle associated with an outbreak of haemorrhagic septicaemia in Sudan, Br. vet. J. 134: 375.PubMedGoogle Scholar
  54. Myint, A. and Carter, G.R., 1989, Prevention of haemorrhagic septicaemia with a live vaccine. Vet. Rec. 124: 508.PubMedCrossRefGoogle Scholar
  55. Myint, A.and Carter. G.R., 1990. Field use of haemorrhagic septicaemia live vaccine. Vet. Rec. 126: 648.Google Scholar
  56. Myint, A., Carter, G.R. and Jones, T.O., 1987, Prevention of experimental haemorrhagic septicaemia with a live vaccine. Vet. Rec. 120: 500.PubMedCrossRefGoogle Scholar
  57. Nagarajan, V., Sundaram, S. and Ramani. K. 1972. Evaluation of the potency of haemorrhagic septicaemia alum precipitated vaccine by mouse protection test, Indian vet.1. 49: 1080.Google Scholar
  58. Nagy. C.K. and Penn. C.W., 1976. Protection of cattle against haemorrhagic septicaemia by capsular antigens of Pasteurella multocida serotypes B and E. Res. vet. Sci. 20: 249.Google Scholar
  59. Namioka, S. and Bruner. D.W., 1963, Serological studies on Pasteurella multocida IV. Type distribution of organisms on the basis of their capsule and O groups, Cornell Vet. 53: 41.PubMedGoogle Scholar
  60. Namioka, S. and Murata,M,, 1961a, Serological studies on Pasteurella multocida I.A. simplified method for capsular typing of the organisms, Cornell Vet. 51: 498.PubMedGoogle Scholar
  61. Namioka. S. and Murata, M., 1961b. Serological studies on Pasteurella multocida TI Charecteristics of the somatic ‘O’ antigen of the organism, Cornell Vet. 51.507.Google Scholar
  62. Namioka, S. and Murata, M., 1961e. Serological studies on Pasteurella multocida ITi ‘O’ antigen analysis of cultures isolated from various animals. Cornell Vet. 51: 522.PubMedGoogle Scholar
  63. Namioka. S. and Murata. M. 1964, Serological studies on Pasteurella multocida IV. Charecterisitcs of the somatic ‘O’ antigen. Cornell vet. 54. 520.Google Scholar
  64. Oreste and Armani, 1887. Cited by Hudson, J.R. in ‘Infections Diseases of Animals: Diseases due to Bacteria, Vo1.2,Pasteurellosis,A.W.,Stablcforth and I.A. Galloway, P. 421, Butterworths Scientific Publications. London.Google Scholar
  65. Ose, E.E. and Muenster, O.A., 1968. A method of evaluating vaccines against Pasteurella multocida, Res. 29: 1863.Google Scholar
  66. Pavri, K.M. and Apte. V.H., 1967, isolation of Pasteurella multocida from a fatal disease of horses and donkeys in India, Vet. Rec. 80: 437.Google Scholar
  67. Perumalpillai, C. and Thamhiayah, V.S., 1957. Outbreaks of haemorrhagic septicaemia in an epizootic form in Ceylon, Ceylon vet. J. 5: 24.Google Scholar
  68. Rhoades, K.R., Heddleston, K.L. and Rebers, P.A., 1967. Can. J. comp. Med., 31: 226.PubMedGoogle Scholar
  69. Rimler, R.B. and Rhoades, K.R., 1987, Serogroup F, a new capsule serogroup of Pasteurella multocida, J. clin. Microbial. 25: 615.Google Scholar
  70. Rimier. R.B. and Wilson. K.R., 1994, Re-examination of Pasteurella multocida serotypes that caused haemorrhagic septicaemia in North America, Vet. Rec. 134: 256.Google Scholar
  71. Roberts. R.S., 1947, An immunological study of Pasteurella septica. J. comp. Path. 57. 261.Google Scholar
  72. Saharee, A.A., Salin, N.B., Rasedee. A. and Jainudcen, M.R., 1962. Haemorrhagic septicaemia carriers among cattle and buffaloes in Malaysia, Proceedings of the International Workshop on Pasteurellosis in Production animals. Aug. 1992. Indonesia ACIAR No. 43: 89.Google Scholar
  73. Sawada, T., Rimier, R.B. and Rhoades. K.R., 1982, indirect haemagglutination test that uses glutaraldehyde fixed sheep erythrocytes sensitised with extract antigens for detection of pasteurella antibody. J. clin. Microbial. 15: 752.Google Scholar
  74. Shigidi, M.T.A., and Mustafa, A.A., 1979, Biochemical and serological studies on Pasteurella multocida isolated from cattle in Sudan, Cornell vet 69: 77.PubMedGoogle Scholar
  75. Singh, N. 1948, Nasal carriers in bovine pasteurellosis, Indian J. vet. Sci.anim. Hush. 18: 261.Google Scholar
  76. Vipulasiri, A.A., Wijewardena, T.G. and De Alwis,M.C.L., 1982, Effect of storage temperature and time on the potency of haemorrhagic septicaemia oil adjuvant vaccine, Sri Lanka vet.1. 30: 19.Google Scholar
  77. Wickremasuriya, U.G.J.S. and Kendaragama, K.M.T., 1982. A case report of haemorrhagic septicaemia in a wild elephant. Sri Lanka vet. J. 30: 34.Google Scholar
  78. Wijewantha, E.A. and Karunaratne, T.G., 1968, Studies on the occurence of Pasteurella multocida in the nasopharynx of healthy cattle, Cornell Vet. 58: 462.Google Scholar
  79. Wijewardana, T.G., De Alwis, M.C.L. and Bastianz, H.L.G., 1986a, Cultural biochemical and pathogenicity studies on strains of Pasteurella multocida isolated from carrier animals and outbreaks of haemorrhagic septicaemia, Sri Lanka vet. J. 34: 43.Google Scholar
  80. Wijewardana, T.G., De Alwis. M.C.L. and Vipulasiri. A.A., 1986b, An investigation into the possible role of the goat as a reservoir host in haemorrhagic septicaemia. Sri Lanka vet. J. 34: 24.Google Scholar
  81. Yadev, M.S. and Ahooja, M.L., 1983. Immunity trials in mice rabbits and calves with oil adjuvant vaccine against haemorrhagic septicaemia. Indian J. anim. Sri. 53. 705.Google Scholar

Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • M. C. L. de Alwis
    • 1
  1. 1.Veterinary Research InstitutePeradeniyaSri Lanka

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