The Choriodecidual Renin Controversy Revisited
Identification of the cell type that contains renin within the uteroplacental unit is important to further research in the physiological function of the renin-angiotensin system at this site. Using an anti-human renal renin monoclonal antibody F37.1A1/Sera-Lab, we found immunopositive staining in cells dispersed throughout the decidual layer of the fetal membranes (Hanssens et al 1994). A small number of immunopositive cells was seen in the chorion laeve while immunopositive cells were found only rarely in the chorionic and in the amnionic mesoderms. These cells have many characteristics of macrophages. They are small, variable in size and shape, and some are loaden with haemosiderin.
KeywordsDouble Staining Fetal Membrane Normal Human Serum Normal Mouse Serum Normal Full Term Pregnan
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