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The Pathophysiology of Ovarian Hyperstimulation Syndrome (OHSS)

A Proposal Role of the Ovarian Derived Prorenin to Angiotensin Cascade (ODPAC)

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Tissue Renin-Angiotensin Systems

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 377))

Abstract

Despite the fact that it was first described over thirty years ago, the factors responsible for (OHSS) have continued to elude investigators. During this time, several theories have been popularized but none have become widely accepted. Recently, it has been suggested that angiotensin II (Ang II) derived from the ovary plays an important role in the development of OHSS (1). This paper will briefly review previous theories and present the results of experiments performed at the University of Southern California School of Medicine that add weight to the notion that ODPAC is involved in OHSS.

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Author information

Authors and Affiliations

  1. Division of Reproductive Endocrinology, University of Southern California School of Medicine, Los Angleles County Women’s and Children’s Hospital, 1240 N. Mission Road, Room 1M2, Los Angeles, Califronia, 90033, USA

    Randy S. Morris, I. Lane Wong, Rogerio A. Lobo, Mark V. Sauer & Richard J. Pauslon

  2. Department of Medicine, University of Southern California School of Medicine, Los Angleles County Women’s and Children’s Hospital, 1240 N. Mission Road, Room 1M2, Los Angeles, Califronia, 90033, USA

    Yung S. Do & Willa A. Hsueh

Authors
  1. Randy S. Morris
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  2. I. Lane Wong
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  3. Yung S. Do
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  4. Willa A. Hsueh
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  5. Rogerio A. Lobo
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  6. Mark V. Sauer
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  7. Richard J. Pauslon
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Editor information

Editors and Affiliations

  1. Institute for Hormone and Fertility Research, University of Hamburg, Hamburg, Germany

    Amal K. Mukhopadhyay Ph.D.

  2. University of Florida, Gainesville, Florida, USA

    Mohan K. Raizada Ph.D.

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© 1995 Springer Science+Business Media New York

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Morris, R.S. et al. (1995). The Pathophysiology of Ovarian Hyperstimulation Syndrome (OHSS). In: Mukhopadhyay, A.K., Raizada, M.K. (eds) Tissue Renin-Angiotensin Systems. Advances in Experimental Medicine and Biology, vol 377. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0952-7_28

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  • DOI: https://doi.org/10.1007/978-1-4899-0952-7_28

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-0954-1

  • Online ISBN: 978-1-4899-0952-7

  • eBook Packages: Springer Book Archive

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