Neuroendocrine Control of Reproduction

  • Richard W. Steger
  • Andrzej Bartke
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 377)


The gametogenic and steroidogenic functions of the ovaries and the testes are controlled by numerous humoral, paracrine and neural signals. Of paramount importance are the pituitary gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH) and, to a lesser extent, prolactin (Prl). The biosynthesis and release of these hormones are regulated by gonadal products and by a number of hypothalamic hormones or modulatory agents. This chapter will review some of the more important mechanisms controlling the release of these hypothalamic substances. Limitations of time and space prevent an exhaustive review of all hypothalamic factors that have been shown to influence LH, FSH and Prl release in view of the fact that the number of endogenous compounds reported to have these actions probably exceeds a 100. However, the number of substances that have proven or at least strongly suspected physiological effects is much smaller.


Luteinizing Hormone Vasoactive Intestinal Peptide Prolactin Secretion Gamma Amino Butyric Acid Prolactin Release 
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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Richard W. Steger
    • 1
  • Andrzej Bartke
    • 1
  1. 1.Department of PhysiologySouthern Illinois University School of MedicineCarbondaleUSA

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