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Tissue Renin-Angiotensin Systems pp 1–14Cite as

The Mammalian Pineal Gland and Reproduction

Controversies and Strategies for Future Research

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 377))

Summary

Evidence for a role of the pineal gland and its major hormonal product, melatonin, in mammalian reproduction has accumulated for over three decades. In sorting through the masses of data pertaining to this issue, certain facts are becoming established. For example, the pineal gland is clearly involved in seasonal reproductive cycles via transduction of daylength (more properly nightlength) information in the form of plasma melatonin rhythms. Specific melatonin receptors are found in the hypothalamus and pituitary pars tuberalis of most of the mammalian species examined thus far. Melatonin’s mode of action on the reproductive axis is quite variable but may, in many cases, involve modulation of gonadotropin-releasing hormone secretion from the median eminence. Clinical evidence continues to support the idea that melatonin may play a role in the timing of puberty.

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Authors and Affiliations

  1. Institute for Hormone and Fertility Research, University of Hamburg, Grandweg 64, 22529, Hamburg, Germany

    James Olcese

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  1. James Olcese
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Editors and Affiliations

  1. Institute for Hormone and Fertility Research, University of Hamburg, Hamburg, Germany

    Amal K. Mukhopadhyay Ph.D.

  2. University of Florida, Gainesville, Florida, USA

    Mohan K. Raizada Ph.D.

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Olcese, J. (1995). The Mammalian Pineal Gland and Reproduction. In: Mukhopadhyay, A.K., Raizada, M.K. (eds) Tissue Renin-Angiotensin Systems. Advances in Experimental Medicine and Biology, vol 377. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0952-7_1

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