Bioeffects of Long-Term Exposures of Animals

  • Arthur W. Guy
Part of the NATO ASI Series book series (NSSA, volume 274)


Between 1962 and 1992 at least 10 major studies have been reported in the literature of the United States on the biological effects of long-term exposure to radiofrequency radiation (RFR) spanning a frequency range of 800 to 9270 MHz. Exposure levels in the studies ranged from 0.48 to 100 mW/cm2 with specific absorption rates (SARs) ranging from 0.075 to 45 W/kg. The studies include the work of Prausnitz and Susskind1 on the life span and pathology in mice; Spalding et al.2 on the body weight, activity, hematopoiesis and life span of mice, Preskorn et al.3 on tumor growth and greater longevity in mice after fetal exposure; Guy et al.4 on ocular and physiologic effects in rabbits; McRee et al.5 on hematological and immunological effects in rabbits; Chou et al.6 on body weight, electroencephalogram (EEG), hematology, and morphology in rabbits; Szmigielski et al.7 on development of spontaneous and benzopyrene-induced skin cancer in mice; Chou et al.8 on body weight, food consumption, and hemotological, morphological, chemical, protein electrophoresis and lymphocyte blast transformation parameters in rabbits; Adair et al.9 on metabolic rate, internal body temperature, blood indices, and thermoregulatory behavior in squirrel monkeys; and Chou et al,10 on general health and longevity, serum chemistries, hematological values, protein electrophoretic patterns, thyroxine, plasma corticosterone levels and histopathological patterns in rats. An overview of each one of these studies is given below, followed by a table summarizing the results.


Exposed Animal Anechoic Chamber Exposed Mouse Microwave Exposure Male Swiss Albino Mouse 
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    C.K. Chou, J.A. Clagett, L.L. Kunz, and A.W. Guy, “Effects of Long-term Radiofrequency Radiation on Immunological Competence and Metabolism,” USAFSAM-TR-85-105, May, Brooks AFB, TX 78235. NTIS publication AD-A169064 (1986).Google Scholar

Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Arthur W. Guy
    • 1
  1. 1.Center for Bioengineering RJ-30University of WashingtonSeattleUSA

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