Abstract
Progressive wasting, weakness, anorexia, and anemia are frequent complications of neoplastic disease.1–4 Decreases in adipose mass constitute the major body losses and exceed losses seen in simple starvation. Decreases in protein constituents of the body, however, are also observed.4–5 The mechanisms for depletion of body energy stores are complex and not adequately explained by anorexia, reduced food consumption, or simply by increased energy utilization by tumor tissue.1,2,6
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Digirolamo, M. (1994). Metabolic Alterations and Lactate Overproduction in Insulin-Resistant States. In: Jacobs, M.M. (eds) Diet and Cancer. Advances in Experimental Medicine and Biology, vol 375. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0939-8_15
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