Possible Role of Neuropeptide Y in Experimental Cancer Anorexia

  • William T. Chance
  • Ambikaipakan Balasubramaniam
  • Sulaiman Sheriff
  • Josef E. Fischer
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 375)


Anorexia and the concomitant depletion of host tissue (cachexia) are commonly observed in cancer patients.1 As many as 75% of cancer patients will exhibit anorexia,2 and this was recognized as early as 1930 as a major contributor to death of cancer patients.3 These aspects of cancer present very difficult problems for both the patient and physician in that the aggressive use of various therapies is severely limited in the cachectic patient.4 In addition, the development of anorexia in cancer patients is associated with increased morbidity and mortality.5


Tumor Inoculation Freely Feeding Ammonia Infusion Plasma Ammonia Concentration Cancer Anorexia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • William T. Chance
    • 1
  • Ambikaipakan Balasubramaniam
    • 2
  • Sulaiman Sheriff
    • 2
  • Josef E. Fischer
    • 2
  1. 1.Department of SurgeryUniversity of Cincinnati Medical Center, Veterans Affairs Medical CenterCincinnatiUSA
  2. 2.Department of SurgeryUniversity of Cincinnati Medical CenterCincinnatiUSA

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