Toward an Identification of Neurotransmitters in the Frog’s Optic Tectum

  • M. E. Sandoval
  • L. Massieu
  • P. Araiza
  • J. Fernandez


The amphibian optic tectum offers an excellent model to study neurotransmission. Using partially isolated nerve endings and slices from frog’s optic tectum, various neurochemical criteria (Na+-dependent transmitter uptake and Ca2+-dependent release, respectively) have been applied to identify neurotransmitters. We looked for the amino acids glutamic acid, aspartic acid, gamma-aminobutyric acid (GABA), and glycine, and for the amines dopamine, norepinephrine, and 5-hydroxytryptamine (serotonin).


Glutamic Acid Nerve Ending Optic Tectum Putative Neurotransmitter Unilateral Enucleation 
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Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • M. E. Sandoval
    • 1
  • L. Massieu
    • 1
  • P. Araiza
    • 1
  • J. Fernandez
    • 1
  1. 1.Instituto de Fisiologia CelularUniversidad Nacional Autónoma de MéxicoMéxico, D.F.México

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