Molecular Epidemiology of Epstein-Barr Virus Obtained from Patients with the Chronic Fatigue Syndrome

  • James F. Jones
  • Susan Baker
  • Joanne Streib
Conference paper


A chronic illness characterized by fatigue, neurological symptoms (headache), paresthesias, tinnitis, dizziness), pharyngitis, cervical (and other sites) lymph node tenderness/swelling myalgia, arthralgia, dyslogia, depressive symptoms, and sleep disturbances, which has prevented the patient from attending school or work 50% of the time over the last six months, has recently been given the label of Chronic Fatigue Syndrome (CFS) (Holmes et al. 1988). Previous work suggested that this illness may be related to immune responses to the Epstein-Barr virus (EBV) (Dubois et al. 1984; Jones et al. 1985; Straus et al. 1985). Subsequently, considerable interest and skepticism has been expressed in the literature concerning whether these patients have an illness, and which infectious agents (if any) are responsible for this syndrome (Buchwald et al. 1987; Holmes et al. 1987).


Chronic Fatigue Syndrome Burkitt Lymphoma Lymphoblastoid Cell Line Infectious Mononucleosis Chronic Fatigue Syndrome Patient 
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Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • James F. Jones
    • 1
  • Susan Baker
    • 1
  • Joanne Streib
    • 1
  1. 1.National Jewish Center for Immunology and Respiratory MedicineDenverUSA

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