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Urolithiasis pp 313-314 | Cite as

Uralyt-U Maintains an Optimal Urinary pH in Patients with Cystinuria

  • U. A. Liberman
  • R. Samuel
  • R. Arie

Abstract

Cystinuria is a rare hereditary disorder of the renal tubular reabsorption of cystine and di-basic amino acids. The predominant clinical problem in these patients is urinary calculi related to the poor solubility of cystine in acid urine. The treatment is directed to prevent and dissolve cystine stones, and can be obtained by dilution and alkalinization of the urine. However, it is difficult to achieve a constant urinary pH higher than 7.4, and large and frequent dosages of drugs are, thus, required. We have measured the therapeutic efficacy of Uralyt-U (hexapotassium hexasodium pentacitrate hydrate complex in the form of granules, one measuring spoon containing 2.5 g) in achieving the desired urinary pH in patients with cystinuria.

Keywords

Poor Solubility Frequent Dosage Urinary Calculus Potassium Citrate Acid Urine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • U. A. Liberman
    • 1
    • 2
  • R. Samuel
    • 1
    • 2
  • R. Arie
    • 1
    • 2
  1. 1.Metabolic DiseasesBeilinson Medical CenterPetah TiqvaIsrael
  2. 2.Sackler Faculty of MedicineTel Aviv UniversityTel AvivIsrael

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