Uralyt-U Maintains an Optimal Urinary pH in Patients with Cystinuria
Cystinuria is a rare hereditary disorder of the renal tubular reabsorption of cystine and di-basic amino acids. The predominant clinical problem in these patients is urinary calculi related to the poor solubility of cystine in acid urine. The treatment is directed to prevent and dissolve cystine stones, and can be obtained by dilution and alkalinization of the urine. However, it is difficult to achieve a constant urinary pH higher than 7.4, and large and frequent dosages of drugs are, thus, required. We have measured the therapeutic efficacy of Uralyt-U (hexapotassium hexasodium pentacitrate hydrate complex in the form of granules, one measuring spoon containing 2.5 g) in achieving the desired urinary pH in patients with cystinuria.