Renal Calculi and Bacterial Adherence: An Ultrastructural Study of Adhesion to Hydroxyapatite Particles by Urinary Tract Pathogens
Urinary tract infections associated with renal calculi are often impossible to cure with antibiotics unless the stone is removed surgically. Calculi may be infection-induced (struvite) or may be formed in idiopathic stone disease (calcium oxalate (CaOx) and/or hydroxyapatite (HAP)). The adhesion of urinary tract pathogens to HAP has not been studied. The present study is aimed at defining the role of different surface fimbriae on the binding of urinary tract isolates to the HAP particles.