The Role of Infection in the Adherence of Urease-Induced Crystals to the Urothelium
Apart from urine supersaturation with respect to magnesium ammonium phosphate and calcium phosphate caused by urease-producing microorganisms, crystal retention is considered to be necessary for the formation of infection stones. This study was performed to investigate the role of the mucous coat, which lines the urothelium, in the adhesion of sterile ureaseinduced crystals, and to determine to what extent the adhesion is influenced by infection.
KeywordsCalcium Phosphate Proteus Mirabilis Phosphate Crystal Ammonium Phosphate Bladder Epithelium
- 1.L Grenabo, H Hedelin, J Hugosson, and S Pettersson, Adherence of ureaseinduced crystals to rat bladder epithelium following acute infection with different uropathogenic microorganisms, J. Urol. (In press, 1988.)Google Scholar