Urolithiasis pp 263-265 | Cite as

The Effect of Glutamic Acid and Aspartic Acid on Calcium-Containing Stones

  • K. Kohri
  • Y. Ishikawa
  • Y. Katayama
  • M. Kodama
  • M. Takada
  • Y. Katoh
  • K. Kataoka
  • M. Iguchi
  • T. Kurita

Abstract

Only glutamic acid (Glu) and aspartic acid (Asp) are acidic amino acids and are negatively charged in ordinary human urine (pH 5.5–6.5). These amino acids and oxalate have a carboxyl group and are suspected to act competitively with each other in Ca stone formation. These factors were considered in the present study which was designed to evaluate the effect of Glu and Asp on Ca stone formation.

Keywords

Calcium Oxalate Urinary Stone Glutamic Pyruvic Transaminase Glutamic Oxalacetic Transaminase Synthetic Urine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    K Kohri, J Garside, and NJ Blacklock, The role of magnesium in calcium oxalate urolithiasis, Br. J. Urol. 61: 107 (1988).PubMedCrossRefGoogle Scholar
  2. 2.
    JB Lian, EL Prien, Jr., MJ Glimcher, and PM Gallop, The presence of protein-bound carboxyglutamic acid in calcium containing renal calculi, J. Clin. Invest. 59: 1151 (1977).PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • K. Kohri
    • 1
  • Y. Ishikawa
    • 1
  • Y. Katayama
    • 1
  • M. Kodama
    • 1
  • M. Takada
    • 1
  • Y. Katoh
    • 1
  • K. Kataoka
    • 1
  • M. Iguchi
    • 1
  • T. Kurita
    • 1
  1. 1.Department of UrologyKinki University School of MedicineOsakaJapan

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