Urolithiasis pp 189-191 | Cite as

Nucleation and Growth Inhibitors of Calcium Oxalate Crystallization

  • A. Rodgers

Abstract

Inhibitors are though to act by influencing one or more of the three basic mechanisms of stone development, namely nucleation, growth, and aggregation or by influencing urine supersaturation (1). The aim of the present study was to examine the inhibitory activity of a number of potential inhibitors of calcium-oxalate crystallization and to characterize such inhibition in terms of nucleation and/or growth.

Keywords

Hyaluronic Acid Methylene Blue Chondroitin Sulphate Calcium Oxalate Calcium Oxalate Monohydrate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    B Finlayson, Renal lithiasis in review, Urol. Clin. North America 1: 181 (1974).Google Scholar
  2. 2.
    JR Burns and B Finlayson, A proposal for a standard reference artificial urine in in vitro urolithiasis experiments, Invest. Urol. 18: 167 (1980).PubMedGoogle Scholar
  3. 3.
    PC Hallson and AG Rose, A new urinary test for stone activity, Br. J. Urol. 50: 442 (1978).PubMedCrossRefGoogle Scholar
  4. 4.
    GW Drach, AD Randolph, and JD Miller, Inhibition of calcium oxalate dihydrate crystallization by chemical modifiers: I. pyrophosphate and methylene blue, J. Urol. 119: 99 (1978).PubMedGoogle Scholar
  5. 5.
    SG Welshman and MG McGeown, A quantitative investigation on the growth of calcium oxalate crystals on potential inhibitors, Br. J. Urol. 44: 677 (1972).PubMedCrossRefGoogle Scholar
  6. 6.
    H Tiselius, Inhibition of calcium oxalate crystal growth in urine during treatment with allopurinol, Br. J. Urol. 52: 189 (1980).PubMedCrossRefGoogle Scholar
  7. 7.
    WG Robertson, M Peacock, and B Nordin, Inhibitors of the growth and aggregation of calcium oxalate crystals in vitro, Clin. Chim. Acta 43: 31 (1973).PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • A. Rodgers
    • 1
  1. 1.Department of Physical ChemistryUniversity of Cape TownRepublic of South Africa

Personalised recommendations