Urolithiasis pp 181-185 | Cite as

Multiple Effects of Amino Acids and Tamm-Horsfall Glycoprotein on the Precipitation of Calcium Oxalate

  • D. Škrtić
  • L. Komunjer
  • H. Füredi-Milhofer
  • V. Hlady
  • M. Marković
  • J. Miculinić

Abstract

Glutamic acid (Glu), tryptophan (Trp), ornithine (Orn), and Tamm-Horsfall glycoprotein (THP) are potential inhibitors or promoters of calcium oxalate (CaOx) precipitation. Glutamine has been identified as a crystallization modifier (1, 2), while Orn and Trp have been found in urines of stone-forming patients (3) but their role in CaOx formation has not yet been systematically investigated. The role of THP in urolithiasis has been disputed: does it promote (4, 5) or inhibit (6, 7) CaOx crystal growth and aggregation?

Keywords

Calcium Oxalate Calcium Oxalate Monohydrate Crystallization Modifier Amino Acid Glutamine Inhibit Crystal Growth 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • D. Škrtić
    • 1
  • L. Komunjer
    • 1
  • H. Füredi-Milhofer
    • 1
  • V. Hlady
    • 1
  • M. Marković
    • 1
  • J. Miculinić
    • 2
  1. 1.“Rudjer Boškovic” InstituteZagreb, CroatiaYugoslavia
  2. 2.Clinical Hospital CenterZagreb, CroatiaYugoslavia

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