Urolithiasis pp 145-146 | Cite as

The Effect of Uric Acid on the Inhibition of Hydroxyapatite Crystal Growth

  • P. Matthews
  • J. W. L. Wilson

Abstract

Hydroxyapatite (HAP) is an important crystal in the pathogenesis of idiopathic calcium urolithiasis. Boyce (1) has reported the presence of small amounts of HAP in all stones analyzed, including so-called “pure” calcium oxalate stones. Hydroxyapatite has the property of induction of heterogeneous nucleation of calcium oxalate monohydrate in vitro (2).

Keywords

Uric Acid Heterogeneous Nucleation Calcium Oxalate Crystal Growth Rate Calcium Oxalate Stone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    WH Boyce, Am. J. Med. 45: 673 (1968).PubMedCrossRefGoogle Scholar
  2. 2.
    JL Meyer, JH Bergert, and LH Smith, Clin. Sci. Molec. Med. 49: 369 (1975).Google Scholar
  3. 3.
    JWL Wilson, PG Werness, and LH Smith, J. Urol. 134: 1255 (1985).PubMedGoogle Scholar
  4. 4.
    MB Tomson and GH Nancollas, Science 200: 1059 (1980).CrossRefGoogle Scholar
  5. 5.
    P Koutsoukos, Z Amjad, MB Tomson, and GH Nancollas, J. Am. Chem. Soc. 102: 1553 (1980).CrossRefGoogle Scholar
  6. 6.
    JN Minuth, DM Musher, and SB Thorfteinsson, J. Infect. Dis. 133: 14 (1976).PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • P. Matthews
    • 1
  • J. W. L. Wilson
    • 1
  1. 1.Department of UrologyQueen’s UniversityKingstonCanada

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