The Effect of Uric Acid on the Inhibition of Hydroxyapatite Crystal Growth
Hydroxyapatite (HAP) is an important crystal in the pathogenesis of idiopathic calcium urolithiasis. Boyce (1) has reported the presence of small amounts of HAP in all stones analyzed, including so-called “pure” calcium oxalate stones. Hydroxyapatite has the property of induction of heterogeneous nucleation of calcium oxalate monohydrate in vitro (2).
KeywordsUric Acid Heterogeneous Nucleation Calcium Oxalate Crystal Growth Rate Calcium Oxalate Stone
- 2.JL Meyer, JH Bergert, and LH Smith, Clin. Sci. Molec. Med. 49: 369 (1975).Google Scholar