Urolithiasis pp 145-146 | Cite as

The Effect of Uric Acid on the Inhibition of Hydroxyapatite Crystal Growth

  • P. Matthews
  • J. W. L. Wilson


Hydroxyapatite (HAP) is an important crystal in the pathogenesis of idiopathic calcium urolithiasis. Boyce (1) has reported the presence of small amounts of HAP in all stones analyzed, including so-called “pure” calcium oxalate stones. Hydroxyapatite has the property of induction of heterogeneous nucleation of calcium oxalate monohydrate in vitro (2).


Uric Acid Heterogeneous Nucleation Calcium Oxalate Crystal Growth Rate Calcium Oxalate Stone 
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Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • P. Matthews
    • 1
  • J. W. L. Wilson
    • 1
  1. 1.Department of UrologyQueen’s UniversityKingstonCanada

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