Physiology of Acid-Base Balance

  • N. A. Kurtzman


The high protein diet consumed by most Western people generates about 60–100 meq of non-volatile acid daily. For homeostasis to be preserved, this acid must be excreted by the kidney. When acid from metabolism (HR) is added to the circulation, it is buffered according to the following reaction:
$$HR + \,NaHCO_3 \to \,NaR + H_2 O + CO_2 $$


Renal Tubular Acidosis Bicarbonate Reabsorption Effective Arterial Blood Volume Alcoholic Ketoacidosis Electrogenic Proton Pump 
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    MG Cogan and FJ Rector, Jr., Acid-base disorders, in: “The Kidney,” BM Brenner and FC Rector, Jr., eds., WB Saunders Co., Philadelphia (1986).Google Scholar
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    MA Knepper and MB Burg, Renal acid-base transport, in: “Diseases of the Kidney,” RW Schrier and CW Gottschalk, eds., Little, Brown and Co., Boston (1988).Google Scholar
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    NA Kurtzman, Renal tubular acidosis: a constellation of syndromes, Hospital Practice 22:173 (1987).PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • N. A. Kurtzman
    • 1
  1. 1.Department of Internal MedicineTexas Tech University Health Sciences CenterLubbockUSA

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