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Urolithiasis pp 125-127 | Cite as

Lipids of Calcium-Oxalate Urinary Stones

  • S. R. Khan
  • P. N. Shevock
  • R. L. Hackett

Abstract

It is generally agreed that crystal nucleation during urolithiasis is heterogeneous. However, the nature of these nucleators is still unknown. Membrane lipids have been histochemically and biochemically demonstrated at physiological as well as pathological calcification sites (1) and have been implicated in nucleation of crystals in a number of bio-mineralization systems. Acidic phospholipids and lipid extracts from calcified tissues have been shown to initiate in vitro calcium phosphate formation from metastable calcium phosphate solutions (1). We have recently demonstrated the presence of lipids in various types of human urinary stones (2). In the present study, we will present additional information regarding lipids of calcium oxalate stones.

Keywords

Calcium Oxalate Choline Phosphatidyl Urinary Stone Ethanolamine Phosphatidyl Calcium Oxalate Stone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    AL Boskey, Current concepts of the physiology and biochemistry of calcification, Clin. Orthopaedics 157: 225 (1981).Google Scholar
  2. 2.
    SR Khan, PN Shevock, and RL Hackett, Presence of lipids in urinary stones: results of preliminary studies, Calcif. Tissue Internat. 42: 91 (1988).CrossRefGoogle Scholar
  3. 3.
    SR Khan, PN Shevock, and RL Hackett, In vitro precipitation of calcium oxalate in the presence of whole matrix or lipid components of urinary stones, J. Urol. 139: 418 (1988).PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • S. R. Khan
    • 1
  • P. N. Shevock
    • 1
  • R. L. Hackett
    • 1
  1. 1.Department of Pathology, College of MedicineUniversity of FloridaGainesvilleUSA

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