Five Years Experience with Oxalyt-CR (Sodium Potassium Citrate) in Calcium-Oxalate Stone Formers
Citrate acts as a potent inhibitor of Ca-oxalate and Ca-phosphate precipitation and the growth of both crystal types. Citrate forms Ca ion complexes which are soluble. The objective of our studies was to determine the efficacy of a sufficient citrate concentration in the urine to reduce the frequency of Ca-oxalate stone formation. This was induced by the administration of Oxalyt-CR (sodium potassium citrate) which represents a new physiological measure without having side effects.