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Urolithiasis pp 845-846 | Cite as

Influence of Single-Dose Alkali Citrate in Hypocitraturic and Hypercalciuric Healthy Subjects

  • M. Butz
  • R. Fitzner
  • G. Schwab
  • H.-J. Dulce

Abstract

Alkali citrates have been widely accepted for prevention of calcium-oxalate (CaOx) urolithiasis (1, 2). Patients’ compliance to a large extent depends on the necessary rules of drug intake. The ingestion of Oxalyt-CR (t.i.d.) in combination with fluids is rather troublesome for working and travelling patients. Urinary lithogenic substances normally increase during the night due to antidiuresis. Thus, the intake of Oxalyt-CR in the evening is of special importance. This study evaluates whether a single dose therapy with Oxalyt-CR has a significant influence on urinary citrate and Ca excretion in cases of hypocitraturic and hypercalciuric non-stone formers.

Keywords

Acid Loading Urinary Citrate Single Dose Therapy Citrate Excretion Recommend Dosage Regimen 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    M Butz, Rational prevention of calcium urolithiasis, Urol. Int. 41:387 (1986).PubMedCrossRefGoogle Scholar
  2. 2.
    CYC Pak, Citrate and renal calculi, Mineral Electrolyte Metabolism 13: 257 (1987).PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • M. Butz
    • 1
  • R. Fitzner
    • 2
  • G. Schwab
    • 1
  • H.-J. Dulce
    • 2
  1. 1.Urologische AbteilungJosef-KrankenhausPaderbornGermany
  2. 2.Institut für Klinische Chemie und Biochemie, Klinikum SteglitzFreie Universität BerlinBerlinGermany

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