A great revolution has taken place in the treatment of urolithiasis in the last few years. Percutaneous lithotripsy, which is minimally invasive, and extracorporeal lithotripsy, which is non-invasive, have made the removal of urinary stones much less morbid than the older, open techniques. Not all stones that need to be removed must be removed surgically. Chemolysis of cystine, struvite, and, particularly, uric acid stones is possible. Dissolving stones by an oral program on an outpatient basis would certainly seem more cost-effective than surgical removal. We undertook a prospective study to examine the effectiveness and safety of dissolving uric acid stones. It has long been known that uric acid stones can be dissolved by oral therapy (1–7). However, these reports tend to be retrospective studies of a few cases, and little can be said about the effectiveness and safety of an oral dissolution program. We present our experience with 21 patients who had relatively lucent, minimally obstructive stones.
KeywordsUric Acid Potassium Citrate Uric Acid Stone Uric Acid Calculus Extracorporeal Lithotripsy
Unable to display preview. Download preview PDF.