Urolithiasis pp 599-600 | Cite as

Experimental and Computed Inhibition of Calcium Oxalate Precipitation

  • A. Rodgers
  • A. Ederies


In order to better understand the influence of certain substances on the nucleation, growth, and aggregation of crystals in urine, researchers have employed several different experimental approaches. Some have elected to carry out their investigations in a stationary test-tube arrangement (1), others have used flow systems (2), and still others have employed a method involving evaporation to produce crystallization (3). Besides these experimental approaches, investigators have demonstrated the usefulness of modelling the ionic equilibria in urine by computer simulation (4). The present study was undertaken to examine the qualitative and quantitative effect of certain ions on calcium oxalate (CaOx) crystallization in a synthetic urine using a combined experimental and theoretical approach.


Calcium Oxalate Quantitative Effect Ionic Equilibrium Oxalate Concentration Citrate Concentration 
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Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • A. Rodgers
    • 1
  • A. Ederies
    • 1
  1. 1.Department of Physical ChemistryUniversity of Cape TownRepublic of South Africa

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