Gentamycin Accelerates Calcium-Oxalate-Monohydrate (COM) Nucleation

  • B. Finlayson
  • S. R. Khan
  • R. L. Hackett


The classical nucleation theory states:
$$ J = A exp \left\{ { - 16\pi s^3 v^2 /3k^3 T^3 (m ln RS)^2 } \right\} $$
with J, the nucleation rate; A, the maximum possible rate of nucleation; RS, the relative supersaturation; s, the liquid-solid interfacial energy; and other terms, system parameters (1). Taking the logarithm, it becomes:
$$ 1n J = 1n A + B/1n^2 RS $$
with B defined by equation (I). It is conventional to consider J to be proportional to the nucleation lag time. Thus, by measuring lag times at various initial RS, it is possible to evaluate A and B and explore nucleation processes.


Nucleation Rate Calcium Oxalate Millipore Filter Calcium Oxalate Monohydrate Normal Urine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    AG Walton, “The Formation and Properties of Precipitates,” Robert E. Kreiger Publishing Co., Huntington, New York (1979).Google Scholar
  2. 2.
    B Finlayson, Calcium stones: some physical and clinical aspects, in: “Calcium Metabolism in Renal Failure and Nephrolithiasis,” DS David, ed., John Wiley & Sons, New York (1977).Google Scholar

Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • B. Finlayson
    • 1
  • S. R. Khan
    • 1
  • R. L. Hackett
    • 1
  1. 1.University of FloridaGainesvilleUSA

Personalised recommendations