Abstract
Dietary oxalate is an important contributor to the body oxalate pool. So far, oxalate absorption from the gut has been studied using intestinal everted sacs or brush-border membrane vesicles. Oxalate absorption has been shown to be a simple diffusion process, and increases linearly with increases in concentration. No studies are available on oxalate uptake by enterocytes isolated from various heights of the intestinal villus-crypt axis. In order to understand the mechanism of oxalate intestinal absorption at a cellular level, oxalate uptake was studied in enterocytes isolated from various heights along the intestinal villus-crypt axis. Enterocytes were isolated sequentially along villus-crypt axis based on the pattern of distribution of sucrase, alkaline phosphatase, and leucine aminopeptidase (1).
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Reference
M Weiser, J. Biol. Chem. 248:2536 (1973).
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© 1989 Springer Science+Business Media New York
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Koul, H.K., Sidhu, M.K., Sidhu, H., Thind, S.K., Nath, R. (1989). Characteristics of Oxalate Uptake Along the Villus-Crypt Axis in Rat Intestine. In: Walker, V.R., Sutton, R.A.L., Cameron, E.C.B., Pak, C.Y.C., Robertson, W.G. (eds) Urolithiasis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0873-5_144
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DOI: https://doi.org/10.1007/978-1-4899-0873-5_144
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