Abstract
Conventional methods used to determine the growth rates of crystal phases which are relevant to urinary stone formation show a number of shortcomings (1). Most of them are time-consuming and require a large test volume. Often, urine has to be highly diluted in order to test the so-called inhibitory activity because a direct application of methodology to undiluted urine is not possible. Results obtained in this way are of questionable physiological relevance.
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References
H Fleisch, Round table discussion on the comparison of models for the study of inhibitory activity in urine, in: “Urolithiasis and Related Clinical Research,” PO Schwille, LH Smith, WG Robertson, and W Vahlensieck, eds., Plenum Press, New York (1985)
W Achilles, Methodische neuerungen des kinetischen gelkristallisationsverfahrens (GKV): automatisierte messung des kalziumoxalatkristallwachsturns durch scanning-microskopphotometrie, Fortschr. Urol. Nephrol. 23:252 (1985).
W Achilles, Crystallization in gel matrices: a new experimental model of calcium stone formation, Contr. Nephrol. 58:59 (1987).
W Achilles and B Ulshöfer, Der einfluss von harnpararnetern auf das kinetische und thermodynamische kristallbildungs-risiko von kalziumoxalat, Fortschr. Urol. Nephrol. 23:216 (1986).
W Achilles et al. Unpublished results.
W Achilles, C Schalk, E Krzyzanek, and D Coors, The effect of urinary constituents of low molecular weight on the crystal growth of calcium oxalate in gel, in: this volume, p. 219.
W Achilles, B Reifenberger, and C Schalk, The effect of urinary macromolecules on the crystal growth of calcium oxalate in gel, in: this volume, p. 69.
W Achilles, C Schalk, and D Schulze. Untersuchungen zum kinetischen und thermodynamischen einfluss von zitrat auf das kristallwachsturn von kalziumoxalat im harn, Fortschr. Urol. Nephrol. 26:230 (1987).
K Tischmann, W Achilles, B Ulshöfer, and G Rodeck, Der einfluss unterschiedlicher, oral verabreichter magnesium-präparate auf das kristallwachstum von kalziumoxalat und andere parameter im menschlichen harn, Fortschr. Urol. Nephrol. 26:230 (1987).
H Iwata, Y Abe, S Nishio, A Wakatsuki, K Ochi, and M Takeuchi, Crystalmatrix interrelations in brushite and uric acid calculi, J. Urol. 135:397 (1986).
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© 1989 Springer Science+Business Media New York
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Achilles, W. (1989). Kinetic Quantification of Crystal Growth in Gel Matrices: An Efficient Model of Urinary Stone Formation. In: Walker, V.R., Sutton, R.A.L., Cameron, E.C.B., Pak, C.Y.C., Robertson, W.G. (eds) Urolithiasis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0873-5_14
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DOI: https://doi.org/10.1007/978-1-4899-0873-5_14
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