Abstract
We recently demonstrated an abnormality in oxalate self-exchange in red blood cells (RBC) of idiopathic stone formers (1, 2) which resides in ‘band-three’ protein and is related to its phosphorylation state (3, 4). A protein cross-reacting with antibodies raised against band-3 protein has been demonstrated in renal tubular cells. Therefore, it is likely that the same RBC defect is also present at the renal level. Since the anion-carrier plays a major role in urinary acidification, we have addressed the problem of a possible defect in urinary acidification in renal stone-forming patients with an abnormal RBC oxalate self-exchange.
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© 1989 Springer Science+Business Media New York
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Gambaro, G., Marchini, F., Bevilacqua, B., Borsatti, A., Baggio, B. (1989). Erythrocyte Abnormality in Oxalate Self-Exchange and Urinary Acidification in Idiopathic Calcium-Oxalate Stone Formers. In: Walker, V.R., Sutton, R.A.L., Cameron, E.C.B., Pak, C.Y.C., Robertson, W.G. (eds) Urolithiasis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0873-5_137
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DOI: https://doi.org/10.1007/978-1-4899-0873-5_137
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