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Seasonal Variations in Urinary Crystalluria and Glutamate Transaminase Levels in Stone Formers and Healthy Normal Subjects

  • P. P. Singh
  • P. Jhamariya
  • A. K. Pendse
  • H. S. Sharma

Abstract

Urinary crystals are considered to be microliths because at any time they can grow into uroliths when conditions are favourable. A more intense and higher prevalence of crystalluria is reported in stone formers (SF) in the summer season as compared to winter (1). Two explanations have been given for this: first, the urine is saturated in summer; and second, there are lower levels of glutamate oxaloacetate transaminase (GOT) and glutamate pyruvate transaminase (GPT) at this time. These enzymes are important since they decrease the glutamic acid level in urine and act as inhibitors. In the present study, we have examined the urinary crystalluria, GOT, and GPT levels in summer (37–39°C) and in winter (5–19°C).

Keywords

Normal Subject Stone Former Calcium Oxalate Glutamate Pyruvate Transaminase Glutamate Concentration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

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    S Frankel, S Reitman, and AC Sonnenwirth, eds., “Gradwoh’s Clinical Laboratory Methods and Diagnosis”, VIIth Edition, Vol. 2, p. 1911 (1970).Google Scholar
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    S Natelson, “Techniques of Clinical Chemistry, IIIrd Edition”, Charles C. Thomas, Springfield, Illinois (1977).Google Scholar
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    R Azoury, S Sarig, N Garti, S Perlberg, AD Randolph, and DGW Drach, Determination of GOT activity on nucleation and crystal growth of calcium oxalate, Urol. Res. 12:223 (1984).PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • P. P. Singh
    • 1
  • P. Jhamariya
    • 1
  • A. K. Pendse
    • 1
  • H. S. Sharma
    • 1
  1. 1.Departments of Biochemistry and SurgeryR.N.T. Medical CollegeUdaipurIndia

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