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Use of rhGM-CSF in Bone Marrow Failure

Is There a Therapeutic Role for GM-CSF in Accidental Radiation Injuries?
  • Joseph H. Antin

Abstract

Radiation accidents resulting in significant injury are, fortunately, uncommon. However, one of the primary manifestations of radiation injury is bone marrow suppression. Depending on the dose of radiation and the manner in which it is received, hematologic effects can be acute and severe or chronic and delayed. The manifestations include aplastic anemia as well as increased risk of leukemia.

Keywords

Aplastic Anemia Myelodysplastic Syndrome Paroxysmal Nocturnal Hemoglobinuria Intermittent Infusion Neutrophil Migration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • Joseph H. Antin
    • 1
  1. 1.Division of Hematology, Department of MedicineBrigham and Women’s HospitalBostonUSA

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