Transfer of Maternal Food Proteins in Milk

  • Paul R. Harmatz
  • Donald G. Hanson
  • Marc Brown
  • Ronald E. Kleinman
  • W. Allan Walker
  • Kurt J. Bloch


For more than 60 years, it has been recognized that nursing infants may develop allergic reactions to substances in the maternal diet.1,2,3 Recent studies demonstrate that, colic,4,5 atopic dermatitis,6,7 and colitis7,8 can be related directly to the presence of a specific protein in the mother’s diet. To understand the basis for these disease processes, investigators have determined dose and molecular character of antigens in milk,6,9,10 probed for a history of atopic disease in the family,10 examined the relationship of antigen-induced disease to skin-test results obtained with the antigen,6 and measured total and cow’s milk-specific IgA antibody titers in breast milk of mothers with symptomatic infants.10 In the latter study, Machtinger and Moss10 found that all breast-fed infants with allergic symptoms had consumed maternal milk with low total and cow’s milk-specific IgA antibody.


Breast Milk Allergy Clin Immunol Maternal Antibody Maternal Circulation Human Breast Milk 
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Copyright information

© Springer Science+Business Media New York 1987

Authors and Affiliations

  • Paul R. Harmatz
    • 1
    • 2
  • Donald G. Hanson
    • 1
    • 2
  • Marc Brown
    • 1
    • 2
  • Ronald E. Kleinman
    • 1
    • 2
  • W. Allan Walker
    • 1
    • 2
  • Kurt J. Bloch
    • 1
    • 2
  1. 1.Departments of Pediatrics and MedicineHarvard Medical SchoolBostonUSA
  2. 2.Combined Program in Pediatric Gastroenterology and Nutrition, and Clinical Immunology and Allergy UnitsMassachusetts General HospitalBostonUSA

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