Cholesterol occurs in human milk as a result of the nature of the lactation process (1,2). When the fat globule is extruded from the mammary cell, it is enveloped by membranes from the endoplasmic reticulum of the cell. The membranes contain cholesterol and are the source of most of the cholesterol in milk. About 15% of the cholesterol is esterified as these compounds are nonpolar, they are found in the hydrophobic core of the fat globule. Cholesterol, relatively hydrophylic because of the free hydroxyl group, is found in the membrane enveloping the globule.
KeywordsBile Acid Human Milk Cholesterol Content Dietary Cholesterol Bile Acid Pool
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