The Effect of Protein Intake on Composition of Weight Gain in Preterm Infants

  • G. Putet
  • J. Rigo
  • B. Salle
  • J. Senterre

Abstract

The comparison between composition of weight gain in the fetus at 32–36 weeks post-conceptional age (1) and weight gain composition of the term infant during the first months of life (2) indicates that the term infant stores much more fat and less water than the fetus. Moreover, published data on weight gain composition of very low birth weight (VLBW) infants fed either human milk (HM) (3–6) or formula (F) (3,4,6) demonstrate that these infants store more fat than the fetus of the same post-conceptional age. It can be assumed that a high fat storage is the normal adaptation to extrauterine life. Alternatively, this high fat storage might also result from the intake of certain nutrients which quantitatively and/or qualitatively may not be adapted to the infant’s immature metabolic capacity. Body composition eventually achieved in the premature infant by 41 weeks will be very different from the body composition of a newly-born term infant.

Keywords

Energy Intake Premature Infant Protein Intake Human Milk Extrauterine Life 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    E.E. Ziegler, A. O’Donnel, S.E. Nelson, S.J. Fomon, Body composition of the reference fetus, Growth 40: 329 (1976).Google Scholar
  2. 2.
    S.J. Fomon, Body composition of the male reference infant during the first year of life, Pediatrics 40: 863–870 (1967).Google Scholar
  3. 3.
    G. Putet, J. Senterre, J. Rigo, B. Salle, Nutrient balance, energy utilization and composition of weight gain in very-low-birth weight infants fed pooled human milk or a preterm formula, J Pediatr 105:79–85 (1984).CrossRefGoogle Scholar
  4. 4.
    R.K. Whyte, R. Haslam, C. Vlainic, Shannons, K. Samulski, D. Campbell, H.S. Bayley, J.C. Sinclair, Energy balance and nitrogen balance in growing low-birth-weight infants fed human milk or formula, Pediatr Res 17:891 (1983).CrossRefGoogle Scholar
  5. 5.
    P. Chessex, B. Reichman, G. Verellen, G. Putet, J.M. Smith, T. Heim, P.R. Swyer, Quality of growth in premature infants fed their own mother’s milk, J Pediatr 102:107 (1983).CrossRefGoogle Scholar
  6. 6.
    B. Reichman, P. Chessex, G. Verellen, G. Putet, J.M. Smith, T. Heim, P.R. Swyer, Dietary composition and macronutrient storage in preterm infants, Pediatrics 72:322–328 (1983).Google Scholar
  7. 7.
    A. Lucas, S.M. Core, T.J. Cole, M.F. Bamford, J.B.F. Dossetor, I. Barr, L. Dicarlo, S. Cork, P.J. Lucas, Multicentre trial on feeding low birth weight infants: effects of diet on early growth, Arch Dis Child 59:722–730 (1984).CrossRefGoogle Scholar
  8. 8.
    K.A. Rronnholm, I. Sipila, M.A. Siimes, Human milk protein supplementation for the prevention of hypoproteinemia without metabolic imbalance in breast milk-fed very low-birth weight infants, J Pediatr 101:243–247 (1982).CrossRefGoogle Scholar
  9. 9.
    J.E. Tyson, R.E. Lasky, C.E. Mize, C.J. Richards, N. Blair-Smith, R. Whyte, A.E. Beer, Growth, metabolic response, and development in very-low birth weight infants fed banked human milk or enriched formula. I. Neonatal findings, J Pediatr 103:95–104 (1983).CrossRefGoogle Scholar
  10. 10.
    S.J. Gross, Growth and biochemical response of preterm infants fed human milk or modified infant formula, N Engl J Med 308:237–241 (1983).CrossRefGoogle Scholar
  11. 11.
    O.G. Brooke, C. Wood, J. Barley, Energy balance, nitrogen balance and growth in preterm infants fed expressed breast milk, a premature infant formula and two low-solute adapted formulas, Arch Dis Child 57:898–904 (1982).CrossRefGoogle Scholar
  12. 12.
    G. Moro, I. Minoli, J. Heininger, M. Cohen, G. Gaull, N.C.R. Raiha, Relationship between protein and energy in the feeding of preterm infants during the first month of life, Acta Paediatr Scand 73:49 (1984).CrossRefGoogle Scholar
  13. 13.
    S. Kashyap, M. Forsyth, C. Zucker, R. Ramakrishman, R.B. Dell, W.C. Heird, Effect of varying protein and energy intakes on growth and metabolic response in low birth weight infants, J Pediatr 108:955–963 (1986).CrossRefGoogle Scholar
  14. 14.
    S.G. Babson, J.L. Bramhall, Diet and growth in the premature infant: the effect of dietary intakes of ash-electrolyte and protein on weight gain and linear growth, J Pediatr 74:890–900 (1969).CrossRefGoogle Scholar
  15. 15.
    N.C.R. Raiha, K. Heinonen, D.K. Rassin, G.E. Gaull, Milk protein quality and quantity in low birth weight infants. I. Metabolic responses and effects on growth, Pediatrics 57:659 (1976).Google Scholar
  16. 16.
    N.W. Svenningsen, M. Lindroth, B. Lindquist, Growth in relation to protein intake of low birth weight infants, Early Hum Dev 6:47 (1982).CrossRefGoogle Scholar
  17. 17.
    G. Putet, N. Fahmy, J. Senterre, J. Rigo, B. Salle, Le lait de femme dans l’alimentation du prématuré, in: Progrès en Néonatologie 4, Minkowski et Relier ed., Karger publisher, pp. 25-32 (1984).Google Scholar
  18. 18.
    G. Putet, A.L. Thelin, G. Philipossian, R. Liardon, M. Arnaud, J. Senterre, B. Salle, Medium chain triglycerides as a source of energy in premature infant, in: Lipids in Modern Nutrition. Raven Press (in press).Google Scholar
  19. 19.
    A. Whitelaw, Subcutaneous fat measurement as an indication of nutrition of the fetus and newborn, in: Nutrition and metabolism of the fetus and infant, H.K.A. Visser ed., Martinus Nijhoff publisher. The Hague, Boston, London, pp. 131-143 (1979).Google Scholar

Copyright information

© Springer Science+Business Media New York 1987

Authors and Affiliations

  • G. Putet
    • 1
  • J. Rigo
    • 2
  • B. Salle
    • 1
  • J. Senterre
    • 2
  1. 1.Department of NeonatologyHopital Edouard HerriotLyonFrance
  2. 2.Department of PediatricsUniversity of LiegeBelgium

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