Biotransformations of Mercury Compounds
The ability of bacteria to convert inorganic and organic mercury compounds to less toxic, volatile elemental mercury is among the most widely found plasmid-determined bacterial phenotypes. It is the best understood microbial metal transformation at levels of analysis from molecular genetics and biochemistry to population biology (4, 14). Mercury compounds are important contaminants in some environmental sites.
KeywordsMercury Compound Detoxification System Mercuric Acetate Mercury Resistance merA Gene
Unable to display preview. Download preview PDF.
- 1.Barkay, T., L. Fouts, and B.H. Olson (1985) A method for the detection of mercury resistance genes in natural bacterial isolates. Appl. Env. Microbiol. 49:686–692.Google Scholar
- 3.Begley, T.P., A.E. Walts, and C.T. Walsh (1986) Mechanistic studies of a protonolytic organomercurial cleaving enzyme: Bacterial organomercurial lyase. Biochemistry 25:7193.Google Scholar
- 4.Foster, T.J. (1987) Genetics and biochemistry of mercury resistance. CRC Crit. Rev, in Microbiol. Google Scholar
- 10.Miller, S.M., D.P. Ballou, V. Massey, C.H. Williams, Jr., and C.T. Walsh (1986) Two-electron reduced mercuric reductase binds Hg(II) to the active site dithiol but does not catalyze Hg(II) reduction. J. Biol. Chem. Google Scholar
- 13.Schultz, P.G., K.G. Au, and C.T. Walsh (1985) Directed mutagenesis of the redox-active disulfide in the flavoenzyme mercuric ion reductase. Biochem. 26:6840–6848.Google Scholar