Advertisement

Transduction Mechanisms in Pacinian Corpuscles

  • Stanley J. BolanowskiJr.

Abstract

Since their detection by Lehman in 1741 (cited by Pallie, et al., 1970), a wealth of information has been obtained on the Pacinian corpuscle, its morphology, chemistry, physiology and the role that it plays in tactile perception. While ostensibly acting as the substrate for the P channel of the somatosensory system (Verrillo, 1966, and Bolanowski and Verrillo, 1982), the corpuscle is also found in the mesentery of cat where it is possible to manipulate them directly. This accessibility has made the corpuscle prototypical for the understanding of mechanotransduction, especially in reference to non-ciliated mechanoreceptors. The relationship among the stimulus, receptor potential and the neural impulse that it generates has been defined, but the actual mechanism underlying transduction and its neural locus are still unknown. The present report focuses on the form of the receptor-potential’s intensity characteristic and the possible neural structures producing it.

Keywords

Compressive Sensi Receptor Potential Intensity Characteristic Pacinian Corpuscle Summate Response 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Andres, K.H., and During, M. von., 1973, Morphology of cutaneous systems, in: “Handbook of Sensory Physiology, Vol. II,” A. Iggo, ed., Springer-Verlag, Berlin, Pp.1–28.Google Scholar
  2. Bolanowski, S.J., Jr., and Verrillo, R.T., 1982, Temperature and criterion effects in a somatosensory subsystem: a neurophysiological and psychophysical study, J. Neurophysiol., 48:836–855.PubMedGoogle Scholar
  3. Bolanowski, S.J., Jr., and Zwislocki, J.J., 1984a, Intensity and frequency characteristics of Pacinian corpuscles. II. Receptor potentials, J. Neurophysiol., 51:812–830.PubMedGoogle Scholar
  4. Bolanowski, S.J., Jr., and Zwislocki, J.J., 1984b, Intensity and frequency characteristics of Pacinian corpuscles. I. Action potentials, J. Neurophysiol., 51:793–811.PubMedGoogle Scholar
  5. Chouchkov, H.N., 1974, An electron microscopic study of the intraepidermal innervation of human glabrous skin, Acta. anat., 88, 84–92.PubMedCrossRefGoogle Scholar
  6. Chouchkov, H.N., 1976, Ultrastructural differences between the preterminal nerve fibers and their endings in the mechanoreceptors, with special reference to their degeneration and mode of uptake of horseradish peroxidase, Prog. Brain Res., 43, 77–87.PubMedCrossRefGoogle Scholar
  7. Diamond, J., Gray, J.A.B., and Inman, D.R., 1958, The depression of receptor potentials in Pacinian corpuscles, J. Physiol., 141, 117–131.PubMedGoogle Scholar
  8. Gottschaldt, K.-M., Fruhstorfer, H., Schmidt, W., and Kraft, I., 1982, Thermosensitivity and its possible fine-structural basis in mechanoreceptors in the beak skin of geese, J. Comp. Neurol., 205, 219–245.PubMedCrossRefGoogle Scholar
  9. Halata, Z., and Munger, B.L., 1980, The ultrastructure of Ruffini and Herbst corpuscles in the articular capsule of domestic pigeon, Anat. Rec., 198, 681–692.PubMedCrossRefGoogle Scholar
  10. Hudspeth, A.J., and Corey, P.P., Sensitivity, polarity and conductance change in the response of vertebrate hair cells to controlled mechanical stimuli, Proc. Natl. Acad. Sci., 74:2407-2411.Google Scholar
  11. Il’inskii, O.B., 1965, Processes of excitation and inhibition in single mechanoreceptors (Pacinian corpuscles), Nature (London)., 208, 351–353.CrossRefGoogle Scholar
  12. Il’inskii, O.B., Volkova, N.K., and Cherepnov, V.L., 1968, Structure and function of Pacinian corpuscles, Fiziol. Zh. SSSR., 54:295, Translation in Neurosciences Translation., 56:637-643.Google Scholar
  13. Lipetz, L.E., 1971, The relationship of physiological and psychological aspects of sensory intensity, in “Handbook of Sensory Physiology, Vol 1.” W.R. Loewenstein, ed., Springer-Verlag, Berlin, Pp. 191–225.Google Scholar
  14. Loewenstein, W.R., 1961, Excitation and inactivation in a receptor membrane, Ann. N.Y. Acad. Sci., 81, 510–534.Google Scholar
  15. Loewenstein, W.R., 1971, Mechano-electric transduction in the Pacinian corpuscle, in: “Handbook of Sensory Physiology, Vol. 1,” W.R. Loewenstein, ed., Springer-Verlag, Berlin, Pp. 269–290.Google Scholar
  16. Pallie, W., Nishi, K, and Oura, C., 1970, The Pacinian corpuscle, its vascular supply and the inner core, Acta Anat. (Basel)., 77, 508–520.PubMedCrossRefGoogle Scholar
  17. Sato, M., 1961, Response of Pacinian corpuscles to sinusoidal vibration. J. Physiol., 159: 391–409.PubMedGoogle Scholar
  18. Spencer, P. S., and Schaumberg, H.H., 1973, An ultrastructural study of the inner core of the Pacinian corpuscle, J. Neurocytol., 2, 217–237.PubMedCrossRefGoogle Scholar
  19. Verrillo, R.T., 1966, Vibrotactile sensitivity and the frequency response of the Pacinian corpuscle, Psychon. Sci., 4, 135–136.Google Scholar
  20. Zwislocki, J.J., 1973, On intensity characteristics of sensory receptors: A generalized function, Kybernetik., 12:169–183.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Stanley J. BolanowskiJr.
    • 1
    • 2
  1. 1.Department of PhysiologyUniv. of Rochester Medical SchoolRochesterUSA
  2. 2.Institute for Sensory ResearchSyracuse UniversitySyracuseUSA

Personalised recommendations