Abstract
Major Depressive Syndrome. An illness episode characterized by either depressed mood, or loss of interest or pleasure. The illness episode should be further characterized by at least five psychobiologic signs of depression, such as weight change, sleep disturbance, psychomotor changes, anergy, feelings of worthlessness, impaired concentration, or recurrent thoughts of death.
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Schiffer, R.B., Klein, R.F., Sider, R.C. (1988). Depressive Syndrome. In: The Medical Evaluation of Psychiatric Patients. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0783-7_6
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