Carbonic Anhydrases in Mammalian Cell Culture and Tumors

  • Patrick J. Venta


This chapter describes some of the work that has been performed with tissue culture cells to understand how carbonic anhydrase (CA) is regulated in various cell types. The advantages of studying genes and gene products in tissue culture are that the treatments of the cells can be completely defined and, in many cases, homogeneous populations of cells can be used without the confounding effects of other cell types. The chapter is not all-inclusive, focusing primarily on the analysis of a number of leukemic cell lines and tissue types that have been studied most frequently or that may be most useful in dissecting the regulation of the CA isozymes and their genes at the molecular level. Many excellent studies using other cell types have not been included.


Carbonic Anhydrase Carbonic Anhydrase Activity Erythroleukemia Cell Myeloid Cell Line Bone Culture 
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Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • Patrick J. Venta
    • 1
  1. 1.Department of Human GeneticsUniversity of Michigan Medical SchoolAnn ArborUSA

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