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Carbonic Anhydrase and Chemoreception in Carotid and Aortic Bodies

  • Sukhamay Lahiri

Abstract

Intracellular pH in eukaryotic cells is maintained more acid than extracellular pH (6.8 vs. 7.4), but it is more alkaline than predicted by electrochemical gradient at equilibrium (reviewed in reference 14). The intracellular pH is therefore maintained by some active process. What critical role the carbonic anhydrases (CAs) play in the maintenance of steady-state cellular cytosolic pH in the glomus cells of carotid and aortic bodies is unclear. It is clear, however, that in dynamic physiological states, where speed of reaction matters, CAs are important.

Keywords

Carotid Body Glomus Cell Peripheral Chemoreceptor Central Chemoreceptor Arterial Chemoreceptor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • Sukhamay Lahiri
    • 1
  1. 1.Department of PhysiologyUniversity of Pennsylvania School of MedicinePhiladelphiaUSA

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