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Carbonic Anhydrase and Chemoreception in Carotid and Aortic Bodies

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The Carbonic Anhydrases

Abstract

Intracellular pH in eukaryotic cells is maintained more acid than extracellular pH (6.8 vs. 7.4), but it is more alkaline than predicted by electrochemical gradient at equilibrium (reviewed in reference 14). The intracellular pH is therefore maintained by some active process. What critical role the carbonic anhydrases (CAs) play in the maintenance of steady-state cellular cytosolic pH in the glomus cells of carotid and aortic bodies is unclear. It is clear, however, that in dynamic physiological states, where speed of reaction matters, CAs are important.

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Lahiri, S. (1991). Carbonic Anhydrase and Chemoreception in Carotid and Aortic Bodies. In: Dodgson, S.J., Tashian, R.E., Gros, G., Carter, N.D. (eds) The Carbonic Anhydrases. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0750-9_30

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  • DOI: https://doi.org/10.1007/978-1-4899-0750-9_30

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-0752-3

  • Online ISBN: 978-1-4899-0750-9

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