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Autonomic Neuropathy in Liver Cirrhosis: Prevalence and Association with Clinical and Laboratory Features

  • S. Giancane
  • M. Bernardi
  • F. Trevisani
  • Paola Emanuela D’Intino
  • Maria Rosa Tamé
  • A. Gasbarrini
  • A. Rimondi
  • G. Gasbarrini
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 298)

Abstract

An impaired autonomic nervous system activity has been described in liver cirrhosis (1,2). Namely, an enhanced sympatho-adrenergic activity has been found in patients with ascites, who also showed an impaired cardiovascular responsiveness to such an adrenergic hypertone (2). Moreover, in these patients the cardiovascular response to the administration of exogenous norepinephrine (1), as well as maneuvers stimulating the adrenergic activity (3), was impaired. Recently, abnormalities of vagal activity have also been described and related to the alcoholic etiology of liver disease (4). It has been suggested that vagal neuropathy may result in an inappropriate, non osmotic secretion of antidiuretic hormone, promoting the appearance of hyponatremia (4), an abnormality which is frequently detectable in advanced liver failure.

Keywords

Upright Posture Blood Pressure Response Autonomic Nervous System Activity Hand Grip Test Deep Breathing Test 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • S. Giancane
    • 1
  • M. Bernardi
    • 1
  • F. Trevisani
    • 1
  • Paola Emanuela D’Intino
    • 1
  • Maria Rosa Tamé
    • 1
  • A. Gasbarrini
    • 1
  • A. Rimondi
    • 1
  • G. Gasbarrini
    • 1
  1. 1.Istituto di Patologia MedicaUniversity of BolognaItaly

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