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Sensory Nerves of the Intestines: Role in Control of Pyloric Region of Dogs

  • Gervais Tougas
  • Hans-D. Allescher
  • John Dent
  • Edwin E. Daniel
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 298)

Abstract

The pyloric region, as described by Torgersen (1) in 1942, consists of a circular thickening of the innermost circular muscle layer found at the junction of the stomach and duodenum. Schulze-Delrieu et al. (2) confirmed the presence of this ring in all mammalian species studied, albeit with some variation in size. This was termed the distal pyloric muscle loop. A second thickened muscular ring, the proximal pyloric muscle loop, has been identified in a number of species, and is connected to the distal pyloric muscle loop by a fan-like arrangement of oblique muscle fibres forming a loop over the distal antrum, running from the greater to the lesser curvature. These two circular muscle loops and their connecting fibres meet at a ridge, or torus, located on the lesser curvature aspect of the stomach. Figure 1 illustrates schematically the muscular anatomy of the human pyloric area.

Keywords

Vagal Stimulation Circular Muscle Myenteric Plexus Cholinergic Nerve Pyloric Sphincter 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Torgersen, J., 1942, The muscular build and movements of the stomach and duodenal bulb, Acta Radiol., 45(suppl):1.Google Scholar
  2. 2.
    Shulze-Delrieu, K. and Wall, J.P., 1984, Determinants of flow across isolated gastroduodenal junctions of cats and rabbits, Am. J. Physiol., 245:G357.Google Scholar
  3. 3.
    Keet, A.D.Jr., 1957, The prepyloric contractions in the normal stomach, Acta Radiologica, 48:413.PubMedCrossRefGoogle Scholar
  4. 4.
    Daniel, E.E., Berezin, I., Allescher, H.D., Manaka, H. and Posey-Danier, V.P., 1990, Morphology of the canine pyloric sphincter in relation to function, Can. J. Physiol. Pharmacol., in press.Google Scholar
  5. 5.
    Code, C.F., 1970, The mystigue of the gastroduodenal junction, Pendic. Rev. Gastroenterol., 2:20.Google Scholar
  6. 6.
    Gonda, T., Daniel, E.E., McDonald, T.J., Fox, J.E.T., Brooks, B.D., Oki, M., 1990, The distribution of galanin-immunoreactive nerves and possible functions of a new neuropeptide in dog gastrointestinal tract. Comparison to VIP, Am. J. Physiol., 256:G884.Google Scholar
  7. 7.
    Wattchow, D.A., Cass, P.J., Furness, J.B., 1987, Abnormalities of peptide-containing nerve fibers in infantile hypertensive pyloric stenosis, Gastroenterology, 92:443.PubMedGoogle Scholar
  8. 8.
    Edin, R., 1980, The vagal control of the pyloric motor function: a physiological and immunohistochemical study in cat and man, Acta Physiol. Scand., 485 (suppl):1.Google Scholar
  9. 9.
    Lidberg, P., Edin, R., Lundberg, J.M., The involvement of substance P in the vagal control of the feline pylorus, Acta Physiol. Scand., 114:307.Google Scholar
  10. 10.
    Allescher, H.-D., Daniel, E. E., Dent, J., Fox, J. E. T., Kostolanska, F., 1988, Extrinsic and intrinsic neural control of pyloric sphincter pressure in the dog, J. Physiol. (Lond.), 401:17.Google Scholar
  11. 11.
    Costa, M., Gabella, G., 1971, Adrenergic innervation of the alimentary canal, Z. Zellforch, 122:357.CrossRefGoogle Scholar
  12. 12.
    Cai, W.Q., Gabella, G., 1984, Structure and innervation of the musculature at the gastroduodenal junction in the guinea pig, J. Anat., 139:93.PubMedGoogle Scholar
  13. 13.
    Daniel, E.E., Posey-Daniel, V.P., 1984, Effect of scorpion venom on structure and function of lower esophageal sphincter (LES) and body circular muscle (BCM) from oppossum, Can. J. Physiol. Pharmacol., 62:360.PubMedCrossRefGoogle Scholar
  14. 14.
    Barajas-Lopes, C., Berezin, I., Daniel, E.E., Huizinga, J.D., 1990, Role of the interstitial cells of Cajal in colon pace-maker generation, Am. J. Physiol., 257:C830.Google Scholar
  15. 15.
    Daniel, E.E., Posey-Daniel, V.P., 1984, Neuromuscular structures in oppossum esophagus: role of interstitial cells of Cajal, Am. J. Physiol., 9:G305.Google Scholar
  16. 16.
    Allescher, H.-D., Daniel, E.E., Fox, J.E.T., Kostolanska, F., 1988, Extrinsic and intrinsic neural control of pyloric sphincter pressure in the dog, J. Physiol. (Lond.), 401:17.Google Scholar
  17. 17.
    Grundy, D., 1988, Vagal control of gastrointestinal function, Bailliere’s Clin. Gastroenterol., 2:23.CrossRefGoogle Scholar
  18. 18.
    Allescher, H.-D., Daniel, E. E, Dent, J., Fox, J. E. T., Kostolanska, F., 1989, Neural reflex of the canine pylorus to intraduodenal acid infusion, Gastroenterology, 96:18.PubMedGoogle Scholar
  19. 19.
    Ormsbee, H.S. III, Fondacaro, J.D., 1985, Action of serotonin on the gastrointestinal tract, Proc. Soc. Exp. Biol. Med., 178:333.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • Gervais Tougas
    • 1
  • Hans-D. Allescher
    • 1
  • John Dent
    • 2
  • Edwin E. Daniel
    • 1
  1. 1.McMaster University Medical CentreHamiltonCanada
  2. 2.The Royal Adelaide HospitalAdelaideAustralia

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