Tumor Prostaglandins and Estrogen Receptors: Prediction of Survival in Patients with Early Breast Cancer
Our initial study of breast tumor prostaglandins concerned their relationship to the spread of the cancer to bone. This investigation, in which patient recruitment was started in 1974 and ended in 1978, was later extended to an examination of the relationship between tumor prostaglandins and patient survival. We found a highly significant inverse relationship (Bennett et al 1980) between the time to death and tumor PG-LM (prostaglandin-like material, so-called because the extracted prostaglandins were bioassayed against PGE2 on rat gastric fundus) (Bennett et al 1973).
KeywordsBreast Cancer Early Breast Cancer Estrogen Receptor Status Human Primary Breast Cancer Estrogen Receptor Content
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