Lipoxygenase Metabolism in the Regulation of Hematopoiesis

  • Alan M. Miller
Part of the GWUMC Department of Biochemistry Annual Spring Symposia book series (GWUN)


In the past 25 years our knowledge of the regulation of the proliferation and differentiation of the cells of the hematopoietic system have grown tremendously. The availability of specific hematopoietic growth factors and of in vitro clonal assays for hematopoietic progenitor cells has made it possible to closely study the interrelationship between cell and cytokine (1,2). This has led to the production of clinically useful recombinant human hematopoietic growth factors (3–6). Despite these rapid advances, as yet little is known about the events that occur in hematopoietic progenitors after they have been stimulated by their appropriate growth factors.


Chronic Lymphocytic Leukemia Caffeic Acid Hematopoietic Growth Factor Lipoxygenase Pathway Lipoxygenase Inhibitor 
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Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • Alan M. Miller
    • 1
  1. 1.Department of Medicine, Division of Medical Oncology and the Gainesville Veterans Affairs Medical CenterUniversity of Florida, College of MedicineGainesvilleUSA

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