Incorporation of Hydroxyeicosatetraenoic Acids into Phospholipid Signaling Pathways
Phosphatidylinositol (PI) and phosphatidylcholine (PC), two major membrane phospholipids (PLs), participate in cell signaling. Their hydrolysis by activated phospholipases produces second messengers, one of which is diacylglycerol (DAG), an activator of protein kinase C which is involved in a variety of cellular responses (1–5).
KeywordsPhosphatidic Acid Inositol Trisphosphate Hydroxyeicosatetraenoic Acid Bovine Pulmonary Artery Endothelial Cell PHOSPHOINOSITIDE Signaling Pathway
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