Immobilization of Proteins via PEG Chains

  • Krister Holmberg
  • Karin Bergström
  • Maj-Britt Stark
Part of the Topics in Applied Chemistry book series (TAPP)


Grafting of poly(ethylene glycol) (or PEG) to solid surfaces has been recognized as a technique for obtaining low protein adsorption and low cell adhesion characteristics.1,2 For instance, PEG coating is reported to give a marked suppression of plasma protein adsorption and platelet adhesion leading to reduced risk of thrombus formation, as demonstrated both in vitro and in vivo.3–5


Cloud Point Protein Adsorption Aqueous Buffer Free Lipase Plasma Protein Adsorption 
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Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • Krister Holmberg
    • 1
  • Karin Bergström
    • 1
  • Maj-Britt Stark
    • 2
  1. 1.Berol NobelStenungsundSweden
  2. 2.Department of HistologyUniversity of GöteborgGöteborgSweden

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