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PEO-Modified Surface-In Vitro, Ex Vivo, and In Vivo Blood Compatibility

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Book cover Poly(Ethylene Glycol) Chemistry

Part of the book series: Topics in Applied Chemistry ((TAPP))

Abstract

Thrombus formation is a serious problem in surgical therapy and clinical application of artificial organs. Therefore, the need for the creation of highly antithrombogenic biomaterials has been increasing. Although a substantial amount of work in the improvement of the blood compatibility of polymeric materials has been carried out, the results are still inconclusive. This is caused partly by the fact that the relationship between surface properties and surface-induced thrombosis has not been thoroughly evaluated.

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Author information

Authors and Affiliations

  1. Department of Pharmaceutics, Center for Controlled Chemical Delivery, University of Utah, Salt Lake City, Utah, 84108, USA

    Ki Dong Park & Sung Wan Kim

Authors
  1. Ki Dong Park
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  2. Sung Wan Kim
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Editor information

Editors and Affiliations

  1. Department of Chemistry, University of Alabama in Huntsville, Huntsville, Alabama, 35899, USA

    J. Milton Harris

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© 1992 Springer Science+Business Media New York

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Park, K.D., Kim, S.W. (1992). PEO-Modified Surface-In Vitro, Ex Vivo, and In Vivo Blood Compatibility. In: Harris, J.M. (eds) Poly(Ethylene Glycol) Chemistry. Topics in Applied Chemistry. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0703-5_18

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  • DOI: https://doi.org/10.1007/978-1-4899-0703-5_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-0705-9

  • Online ISBN: 978-1-4899-0703-5

  • eBook Packages: Springer Book Archive

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