Basic Statistical Principles

  • Joel B. Greenhouse
  • Brian W. Junker
Part of the Critical Issues in Psychiatry book series (CIPS)


In a randomized controlled clinical trial for the prevention of the recurrence of depression, it is reported that imipramine is more effective than lithium or placebo in delaying the recurrence of a depressive episode. In another study, a randomized controlled clinical trial of the comparative efficacy of interpersonal therapy, cognitive behavioral therapy, imipramine, and placebo for the treatment of depression, it is found that the psychotherapies and the drug are almost equally effective. In a nonrandomized comparative study, it is reported that depressed patients have a decrease in rapid-eye movement latency relative to healthy subjects. As consumers of statistics there are many questions we should ask about these studies, including: How were these conclusions reached? What do these conclusions mean? and How should we evaluate the merits of these studies and their results?


Explanatory Variable Depressed Patient Conditional Distribution Early Recurrence Plasma Cortisol Level 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • Joel B. Greenhouse
    • 1
  • Brian W. Junker
    • 1
  1. 1.Department of StatisticsCarnegie-Mellon UniversityPittsburghUSA

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