Abstract
The neuropsychological assessment of psychiatric patients is often complicated by the medications or treatments that are being administered. The clinician must discern whether impaired test performance reflects disease-related or iatrogenically induced cognitive deficit. In this chapter we review the literature investigating the effects of neuroleptics, antidepressants, and lithium on the neuropsychological test performance of psychiatric patients. For a review of the cognitive effects of these medications in normal subjects we refer the reader to Judd, Squire, Butters, Salmon, and Palier (1987). This review focuses on measures that are commonly used in the context of neuropsychological assessment. It is organized by medication and particular cognitive function or test that might be affected. At the end of each section we propose some clinical guidelines and theoretical hypotheses that can be generated on the basis of this literature.
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Medalia, A., Gold, J. (1992). Psychoactive Drugs in the Psychotic and Affective Disorders. In: Puente, A.E., McCaffrey, R.J. (eds) Handbook of Neuropsychological Assessment. Critical Issues in Neuropsychology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0682-3_17
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