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Schizophrenic Disorders

  • Elaine Walker
  • Marsha Lucas
  • Richard Lewine
Part of the Critical Issues in Neuropsychology book series (CINP)

Abstract

The conceptualization of schizophrenia as a brain disorder is long-standing. Kraepelin (1919/1971) emphasized the gradual cognitive deterioration in schizophrenia and argued that this “dementia” was organically based. Although Bleuler (1950) viewed “associative disturbance” as the core symptom in schizophrenia, like Kraepelin he presumed the symptoms of schizophrenia were a manifestation of underlying organic impairment. Since the times of Kraepelin and Bleuler, interest in organic determinants of schizophrenia has waxed and waned. Most recently, we have entered a new era of biological research on the disorder. The renewed concern with biological factors was, in part, spawned by the increasing sophistication of available techniques for assessing brain structure and function.

Keywords

Negative Symptom Schizophrenic Patient Psychiatric Patient Tardive Dyskinesia Neuropsychological Assessment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Adams, H., Malatesta, V., Brantley, P., & Turkat, I. (1981). Modification of cognitive processes: A case study of schizophrenia. Journal of Consulting and Clinical Psychology, 49, 460–464.PubMedCrossRefGoogle Scholar
  2. Adams, K. M., Jacisin, J. J., Brown, G. G., Boulos, R. S., & Silk, S. D. (1984). Neurobehavioral deficit and computed tomographic abnormalities in three samples of schizophrenic patients. Perceptual and Motor Skills, 59, 115–119.PubMedCrossRefGoogle Scholar
  3. Andreasen, N. C., Nasrallah, H. A., Dunn, S. C., Olson, S. C., Grove, W. M., Ehrhardt, J. C., Coffman, J. A., & Crossett, J. H. W. (1986). Structural abnormalities in the frontal system in schizophrenia. Archives of General Psychiatry, 43, 136–147.PubMedCrossRefGoogle Scholar
  4. Andreasen, N. C., Dennert, J. W., Olsen, S. A., & Damasio, A. R., (1982a). Hemispheric asymmetries and schizophrenia. American Journal of Psychiatry, 139, 427–430.PubMedGoogle Scholar
  5. Andreasen, N. C., Smith, M. R., Jacoby, C. G., Dennert, J. W., & Olsen, S. A. (1982b). Ventricular enlargement in schizophrenia: Definition and prevalence. American Journal of Psychiatry, 139, 292–302.PubMedGoogle Scholar
  6. Aylward, E., Walker, E., & Bettes, B. (1984). Intelligence in schizophrenia: A review and metaanalysis of the literature. Schizophrenia Bulletin, 10, 430–459.PubMedCrossRefGoogle Scholar
  7. Bankier, R. G. (1985). Third ventricle size and dementia in schizophrenia. British Journal of Psychiatry, 147, 241–245.PubMedCrossRefGoogle Scholar
  8. Bashore, T. (1981). Vocal and manual reaction time estimate of interhemispheric reaction time. Psychological Bulletin, 89, 352–368.PubMedCrossRefGoogle Scholar
  9. Beaumont, J. G., & Dimond, J. S. (1973). Brain disconnection and schizophrenia. British Journal of Psychiatry, 123, 661–662.PubMedCrossRefGoogle Scholar
  10. Benson, D. F., & Stuss, D. T. (1982). Motor abilities after frontal leukotomy. Neurology, 32, 1353–1357.PubMedCrossRefGoogle Scholar
  11. Berman, K. E, Weinberger, D. R., Shelton, R. C., & Zec, R. F. (1987). A relationship between anatomical and physiological brain pathology in schizophrenia: Lateral cerebral ventricular size predicts cortical blood flow. American Journal of Psychiatry, 144, 1277–1282.PubMedGoogle Scholar
  12. Bleuler, E. (1950). Dementia praecox or the group of schizophrenias. New York: International Universities Press.Google Scholar
  13. Boucher, M. L., Dewan, M. J., Donnelly, M. P., Pandurangi, A. K., Barteil, K., Diamond, T., & Major, L. F. (1986). Relative utility of three indices of neuropsychological impairment in a young, chronic schizophrenic population. Journal of Nervous and Mental Disease, 174, 44–46.PubMedCrossRefGoogle Scholar
  14. Bracha, S. (1987). Asymmetric rotational (circling) behavior. A dopamine-related asymmetry: Preliminary findings in unmedicated and never-medicated schizophrenic patients. Biological Psychiatry, 22, 105–114.CrossRefGoogle Scholar
  15. Carr, E. G., & Wedding, D. (1984). Neuropsychological assessment of cerebral ventricular size in chronic schizophrenics. International Journal of Clinical Neuropsychology, 6, 106–111.Google Scholar
  16. Chapman, L. J., & Chapman, J. P. (1978). The measurement of differential deficit. Journal of Psychiatric Research, 14, 303–311.PubMedCrossRefGoogle Scholar
  17. Chelune, G. J., Heaton, R. K., Lehman, R. A. W, & Robinson, A. (1979). Level versus pattern of neuropsychological performance among schizophrenic and diffusely brain-damaged patients. Journal of Consulting and Clinical Psychology, 47, 155–163.PubMedCrossRefGoogle Scholar
  18. Craft, S., Willerman, L., & Bigler, E. D. (1987). Callosal dysfunction in schizophrenia and schizoaffective disorder. Journal of Abnormal Psychology, 96, 205–213.PubMedCrossRefGoogle Scholar
  19. Crow, T. J. (1980). Molecular pathology of schizophrenia: More than one disease process? British Medical Journal, 280, 66–68.PubMedCrossRefGoogle Scholar
  20. Davila, R., Manero, E., Zumarraga, M., Andia, I., Schweitzer, J. W, & Friedhoff, A. J. (1988). Plasma homovanillic acid as a predictor of response to neuroleptics. Archives of General Psychiatry, 45, 564–567.PubMedCrossRefGoogle Scholar
  21. Dean, R. S., Gray, J. W., & Seretny, M. L. (1987). Cognitive aspects of schizophrenia and primary affective depression. The International Journal of Clinical Neuropsychology, 9, 33–35.Google Scholar
  22. DeMeyer, M. K., Gilmor, R., Hendrie, H., DeMeyer, W. E., and Franco, J. N. (1984). Brain densities in treatment-resistant schizophrenic and other psychiatric patients. Journal of Operational Psychiatry, 15, 9.Google Scholar
  23. Dewan, M. J., Pandurangi, A. K., Lee, S. H., Ramachandran, T., Levy, B., Boucher, M., Yozawitz, A., & Major, L. (1986). A comprehensive study of chronic schizophrenic patients, I. Quantitative computed tomography: Cerebral density, ventricle and sulcal measures. Acta Psychiatrica Scandinavica, 73, 152–160.PubMedCrossRefGoogle Scholar
  24. Donnelly, E. F. (1984). Neuropsychological impairment and associated intellectual functions in schizophrenic and other psychiatric patients. Biological Psychiatry, 19, 815–824.PubMedGoogle Scholar
  25. Donnelly, E. E, Weinberger, D. R., Waldman, I. N., & Wyatt, R. J. (1980). Cognitive impairment associated with morphological brain abnormalities on computed tomography in chronic schizophrenic patients. Journal of Nervous and Mental Disease, 168, 305–308.PubMedCrossRefGoogle Scholar
  26. Erickson, R. C., & Binder, L. M. (1986). Cognitive deficits among functionally psychotic patients: A rehabilitative perspective. Journal of Clinical and Experimental Neuropsychology, 8, 257–274.PubMedCrossRefGoogle Scholar
  27. Flor-Henry, P. (1976). Lateralized temporal limbic dysfunction and psychopathology. Annals of the New York Academy of Science, 280, 777–795.CrossRefGoogle Scholar
  28. Freedman, B. J. (1974). The subjective experience of perceptual and cognitive disturbances in schizophrenia. Archives of General Psychiatry, 30, 333–340.PubMedCrossRefGoogle Scholar
  29. Freeland, J., & Puente, A. E. (1984). Relative efficacy of the Luria-Nebraska Neuropsychological Battery and the Wechsler Adult Intelligence Scale in discriminating schizophrenics with and without brain damage. International Journal of Neuropsychology, 6, 261–263.Google Scholar
  30. Galaburda, A. M., LeMay, M., Kemper, T. L., & Geschwind, N. (1978). Right-left asymmetries in the brain. Science, 199, 852–856.PubMedCrossRefGoogle Scholar
  31. Goldberg, T., Weinberger, D. R., & Berman, K. (1987). Further evidence for dementia of the prefrontal type in schizophrenia? A controlled study of teaching the Wisconsin Card Sorting Test. Archives of General Psychiatry, 44, 1008–1014.PubMedCrossRefGoogle Scholar
  32. Golden, C. J., Graber, B., Coffman, J., Berg, R. A., Newlin, D. B., & Bloch, S. (1981). Structural brain deficits in schizophrenia. Archives of General Psychiatry, 38, 1014–1017.PubMedCrossRefGoogle Scholar
  33. Golden, C. J., Moses, J. A., Zelazowski, R., Graber, B., Zatz, L. M., Horvath, J. B., & Berger, P. A. (1980). Cerebral ventricular size and neuropsychological impairment in young chronic schizophrenics. Archives of General Psychiatry, 37, 619–623.PubMedCrossRefGoogle Scholar
  34. Goldstein, G. (1986). The neuropsychology of schizophrenia. In I. Grant & K. Adams (Eds.), Neuropsychological Assessment of Neuropsychiatric Disorders (pp. 147–171). New York: Oxford University Press.Google Scholar
  35. Green, E. J. (1985). Interhemispheric coordination and focused attention in chronic and acute schizophrenia. British Journal of Clinical Psychology, 24, 197–204.PubMedCrossRefGoogle Scholar
  36. Green, M., & Walker, E. (1984). Susceptibility to backward masking in schizophrenics with positive versus negative symptoms. American Journal of Psychiatry, 141, 1273–1275.PubMedGoogle Scholar
  37. Green, M., & Walker, E. (1985). Neuropsychological performance and positive and negative symptoms in schizophrenia. Journal of Abnormal Psychology, 94, 460–470.PubMedCrossRefGoogle Scholar
  38. Green, P. (1978). Defective interhemispheric transfer in schizophrenia. Journal of Abnormal Psychology, 87, 472–480.PubMedCrossRefGoogle Scholar
  39. Green, P. (1987). Interference between the two ears in speech comprehension and the effect of an earplug in psychiatric and cerebral-lesioned patients. Cerebral Dynamics, Laterality and Psychopathology, 287-298.Google Scholar
  40. Green, P., Hallett, S., & Hunter, M. (1983). Abnormal interhemispheric integration and hemispheric specialization in schizophrenia. In P. Flor-Henry & J. Gruzelier (Eds.), Laterality and psychopathology (pp. 131–150). Amsterdam: Elsevier.Google Scholar
  41. Green, P., & Kotenko, V (1980). Superior speech comprehension under monaural versus binaural listening conditions. Journal of Abnormal Psychology, 89, 399–408.PubMedCrossRefGoogle Scholar
  42. Gruzelier, J. (1984). Hemispheric imbalances in schizophrenia. International Journal of Psychophysiology, 1, 227–240.PubMedCrossRefGoogle Scholar
  43. Hallett, S., Quinn, D., & Hewitt, J. (1986). Defective interhemispheric integration and anomalous language lateralization in children at risk for schizophrenia. The Journal of Nervous and Mental Disease, 174, 418–427.PubMedCrossRefGoogle Scholar
  44. Hatta, T., Yamamoto, M., & Kawabata, Y. (1984). Functional hemispheric differences in schizophrenia: Interhemispheric transfer deficit of selective hemisphere dysfunction? Biological Psychiatry, 19, 1027–1036.PubMedGoogle Scholar
  45. Heaton, R. K. (1979). Neuropsychological impairment with schizophrenia vs. acute and chronic cerebral lesions. Journal of Clinical Psychology, 35, 46–53.PubMedCrossRefGoogle Scholar
  46. Heaton, R. K., Baade, L. E., & Johnson, K. L. (1978). Neuropsychological test results associated with psychiatric disorders in adults. Psychological Bulletin, 85, 141–162.PubMedCrossRefGoogle Scholar
  47. Jernigan, T. L., Zatz, L. M., Moses, J. A., & Cardellino, J. P. (1982a). Computed tomography in schizophrenics and normal volunteers. II: Cranial asymmetry. Archives of General Psychiatry, 39, 771–773.PubMedCrossRefGoogle Scholar
  48. Jernigan, T. L., Zatz, L. M., Moses J. A., & Berger, P. A. (1982b). Computed tomography in schizophrenics and volunteers. I: Fluid volume. Archives of General Psychiatry, 39, 765–770.PubMedCrossRefGoogle Scholar
  49. Johnstone, E. C., Crow, T. J., Frith, C. D., Husband, J., & Kreel, L. (1976). Cerebral ventricular size and cognitive impairment in chronic schizophrenia. Lancet, 2, 924–926.PubMedCrossRefGoogle Scholar
  50. Kelsoe, J. R., Cadet, J. L., Pickar, D., & Weinberger, D. R. (1988). Quantitative neuroanatomy in schizophrenia. Archives of General Psychiatry, 45, 533–541.PubMedCrossRefGoogle Scholar
  51. Kemali, D., Maj, M., Galderisi, S., & Salvati, A. (1987). Clinical, biological, and neuropsychological features associated with lateral ventricular enlargement in DSM-III schizophrenic disorder. Psychiatry Research, 21, 137–149.PubMedCrossRefGoogle Scholar
  52. Kolakowska, T., Williams, A. Q, Jambor, K., & Ardern, M. (1985). Schizophrenia with good and poor outcome: III. Neurological “soft” signs, cognitive impairment and their clinical significance. British Journal of Psychiatry, 146, 348–357.PubMedCrossRefGoogle Scholar
  53. Kolb, B., & Whishaw, I. Q. (1983). Performance of schizophrenic patients on tests sensitive to left or right frontal, temporal, or parietal function in neurological patients. Journal of Nervous and Mental Disease, 171, 435–443.PubMedCrossRefGoogle Scholar
  54. Kraepelin, E. (1971). Dementia praecox and paraphrenia. Huntington, N.Y.: Krieger.Google Scholar
  55. Kugler, B. T., & Caudrey, D. J. (1983). Phoneme discrimination in schizophrenia. British Journal of Psychiatry, 142, 53–59.PubMedCrossRefGoogle Scholar
  56. Langell, M. E., Purisch, A. D., & Golden, C. J. (1987). Neuropsychological differences between paranoid and nonparanoid schizophrenics on the Luria-Nebraska Battery. International Journal of Clinical Neuropsychology, 9, 88–95.Google Scholar
  57. Largen, J. W, Smith, R. C., Calderon, M., Baumgartner, R., Lu, R., Schoolar, J. C., & Ravichandran, G. K. (1984). Abnormalities of brain structure and density in schizophrenia. Biological Psychiatry, 19, 991–1013.PubMedGoogle Scholar
  58. Lawson, W. B., Waldman, I. N., & Weinberger, D. R. (1988). Schizophrenic dementia: Clinical and computed axial tomography correlates. Journal of Nervous and Mental Disease, 176, 207–212.PubMedCrossRefGoogle Scholar
  59. Lenzer, I.I. (1980). Halstead-Reitan Test Battery: A problem of differential diagnosis. Perceptual and Motor Skills, 50, 611–630.PubMedCrossRefGoogle Scholar
  60. Levander, S. E., Bartfai, A., & Schalling, D. (1985). Regional cortical dysfunction in schizophrenic patients studied by computerized neuropsychological methods. Perceptual and Motor Skills, 61, 479–495.PubMedCrossRefGoogle Scholar
  61. Lewis, G., Golden, C. J., Purisch, A. D., & Hammeke, T. A. (1979). The effects of chronicity of disorder and length of hospitalization on the standardized version of Luria’s Neuropsychological Battery in a schizophrenic population. Clinical Neuropsychology, 1, 13–18.Google Scholar
  62. Lewis, R. F., Nelson, R. W, & Eggertsen, C. (1979). Neuropsychological test performances of paranoid schizophrenic and brain-damaged patients. Journal of Clinical Psychology, 35, 54–59.PubMedCrossRefGoogle Scholar
  63. Liddle, P. F. (1987). Schizophrenic syndromes, cognitive performance and neurological dysfunction. Psychological Medicine, 17, 49–57.PubMedCrossRefGoogle Scholar
  64. Luchins, D. J., Weinberger, D. R., & Wyatt, R. J. (1979). Schizophrenia: Evidence for a subgroup with reversed cerebral asymmetry. Archives of General Psychiatry, 36, 1309–1311.PubMedCrossRefGoogle Scholar
  65. Luchins, D. J., Weinberger, D. R., & Wyatt, R. J. (1982). Schizophrenia and cerebral asymmetry detected by computed tomography. American Journal of Psychiatry, 139, 753–757.PubMedGoogle Scholar
  66. Luchins, D.J., Lewine, R., & Meltzer, H. (1984). Lateral ventricular size, psychopathology, and medication response in psychoses. Biological Psychiatry, 19, 29–44.PubMedGoogle Scholar
  67. Maj, M. (1986). Neuropsychological functioning in schizoaffective disorder, depressed type. Acta Psychiatrica Scandinavica, 74, 524–528.PubMedCrossRefGoogle Scholar
  68. Malec, J. (1978). Neuropsychological assessment of schizophrenia versus brain damage: A review. Journal of Nervous and Mental Disease, 166, 507–516.PubMedCrossRefGoogle Scholar
  69. Mathew, R. J., Partain, C. L., Prakash, R., Kulkarni, M. V, Logan, T. P, & Wilson, W. H. (1985). A study of the septum pellicidum and corpus callosum in schizophrenia with MR imaging. cta Psychiatrica Scandinavica, 72, 414–421.CrossRefGoogle Scholar
  70. Mayer, M., Alpert, M., Stastny, P., Perlick, D., & Empfield, M. (1985). Multiple contributions to clinical presentation of flat affect in schizophrenia. Schizophrenia Bulletin, 11, 420–426.PubMedCrossRefGoogle Scholar
  71. Moses, J. A. (1984). The effect of presence or absence of neuroleptic medication treatment on Luria-Nebraska Neuropsychological Battery performance in a schizophrenic population. International Journal of Clinical Neuropsychology, 6, 249–251.Google Scholar
  72. Moses, J. A., Cardellino, J. P., & Thompson, L. L. (1983). Discrimination of brain damage from chronic psychosis by the Luria-Nebraska Neuropsychological Battery: A closer look. Journal of Consulting and Clinical Psychology, 51, 441–449.PubMedCrossRefGoogle Scholar
  73. Myslobodsky, M. S. (1985). Cognitive impairment in patients with tardive dyskinesia. Journal of Nervous and Mental Disease, 173, 156–160.PubMedCrossRefGoogle Scholar
  74. Nasrallah, H. A., McCalley-Whitters, M., & Jacoby, C. G. (1982). Cortical atrophy in schizophrenia and mania: A comparative CT study. Journal of Clinical Psychiatry, 43, 439–441.PubMedGoogle Scholar
  75. Nasrallah, H. A., Kuperman, S., Hamra, B., & McCalley-Whitters, M. (1983). Clinical differences between schizophrenic patients with and without large cerebral ventricles. Journal of Clinical Psychiatry, 44, 407–409.PubMedGoogle Scholar
  76. Nasrallah, H. A., Andreasen, N. C., Coffman, J. A., Olsen, S. C., Dunn, J. D, Ehrhardt, J. C., & Chapman, S. M. (1986). A controlled magnetic resonance imaging study of corpus callosum thickness in schizophrenia. Biological Psychiatry, 21, 274–282.PubMedCrossRefGoogle Scholar
  77. Neale, J., & Oltmanns, T. (1980). Schizophrenia. New York: Wiley.Google Scholar
  78. Nyman, H., Nyback, H., Wiesel, F. A., Oxenstierna, G., & Schalling, D. (1986). Neuropsychological test performance, brain morphological measures and CSF monoamine metabolites in schizophrenic patients. Acta Psychiatrica Scandinavica, 74, 292–301.PubMedCrossRefGoogle Scholar
  79. Obiols, J. E., Marcos, T., & Salamero, M. (1987). Ventricular enlargement and neuropsychological testing in schizophrenia. Acta Psychiatrica Scandinavica, 76, 199–202.PubMedCrossRefGoogle Scholar
  80. Pandurangi, A. K., Dewan, M. J., Boucher, M., Levy, B., Ramachandran, T., Bartell, K., Bick, P. A., Phelps, B. H., & Major, L. (1986). A comprehensive study of schizophrenic patients. II: Biological, neuropsychological, and clinical correlates of CT abnormality. Acta Psychiatrica Scandinavica, 73, 161–171.PubMedCrossRefGoogle Scholar
  81. Pandurangi, A. K., Dewan, M. J., Lee, S. H., Ramachandran, T, Levy, B. F., Boucher, M., Yozawitz, A., & Major, L. (1984). The ventricular system in chronic schizophrenic patients: A controlled computed tomographic study. British Journal of Psychiatry, 144, 172–176.PubMedCrossRefGoogle Scholar
  82. Puente, A. E., Tune, L., Orrell, T, & Hendrickson, J. (1984). The relationship between the LNNB scale scores and neuroleptic dosage levels in schizophrenics. International Journal of Clinical Neuropsychology, 7, 69.Google Scholar
  83. Purisch, A. D., Golden, C. J., & Hammeke, T. A. (1978). Discrimination of schizophrenic and braininjured patients by a standard version of Luna’s Neuropsychological Tests. Journal of Consulting and Clinical Psychology, 46, 1266–1273.PubMedCrossRefGoogle Scholar
  84. Rieder, R. O., Donnelly, E. E, Herdt, J. R., & Waldman, I. N. (1979). Sulcal prominence in young chronic schizophrenic patients: CT scan findings associated with impairment on neuropsychological tests. Psychiatry Research, 1, 1–8.PubMedCrossRefGoogle Scholar
  85. Rieder, R. O., Mann, L. S., Weinberger, D. R., van Kammen, D. P., & Post, R. M. (1983). Computed tomographic scans in patients with schizophrenia, schizoaffective, and bipolar affective disorder. Archives of General Psychiatry, 40, 735–739.PubMedCrossRefGoogle Scholar
  86. Rosenthal, R., & Bigelow, L. B. (1972). Quantitative brain measurements in chronic schizophrenics. British Journal of Psychiatry, 121, 259–264.PubMedCrossRefGoogle Scholar
  87. Schneider, S. J. (1983). Multiple measures of hemispheric dysfunction in schizophrenia and depression. Psychological Medicine, 13, 287–297.PubMedCrossRefGoogle Scholar
  88. Seeman, M. V. (1985). Clinical and demographic correlates of neuroleptic response. Canadian Journal of Psychiatry, 30, 243–245.Google Scholar
  89. Selin, C. L., & Gottschalk, L. A. (1983). Schizophrenia, conduct disorder and depressive disorder: Neuropsychological, speech sample and EEG results. Perceptual and Motor Skills, 57, 427–444.PubMedCrossRefGoogle Scholar
  90. Shelly, C., & Goldstein, G. (1983). Discrimination of chronic schizophrenia and brain damage with the Luria-Nebraska Battery: A partially successful replication. Clinical Neuropsychology, 5, 82–85.Google Scholar
  91. Shelton, R. C., & Weinberger, D. R. (1986). X-ray computerized tomography studies in schizophrenia: A review and synthesis. In H. A. Nasrallah & D. R. Weinberger (Eds.), Handbook of schizophrenia (Vol. I, pp. 207–250). Amsterdam: Elsevier.Google Scholar
  92. Shimkunas, A. (1978). Hemispheric asymmetry and schizophrenic thought disorder. In S. Schwartz (Ed.), Language and cognition in schizophrenia (pp. 193–236). New York: Wiley.Google Scholar
  93. Silverstein, M. L., & Arzt, A. T. (1985). Neuropsychological dysfunction in schizophrenia: Relation to associative thought disorder. Journal of Nervous and Mental Disease, 173, 341–346.PubMedCrossRefGoogle Scholar
  94. Silverstein, M. L., & Zerwic, M. J. (1985). Clinical psychopathologic symptoms in neuropsychologically impaired and intact schizophrenics. Journal of Consulting and Clinical Psychology, 53, 267–268.PubMedCrossRefGoogle Scholar
  95. Smith, R. C., Baumgartner, R., & Calderon, M. (1987). Magnetic resonance imaging studies of the brains of schizophrenic patients. Psychiatry Research, 20, 33–46.PubMedCrossRefGoogle Scholar
  96. Steinhauer, S., & Zubin, J. (1982). Vulnerability to schizophrenia information processing in the pupil and event-related potentials. In I. Hanin & E. Usdin (Eds.), Biological markers in psychiatry and neurology (pp. 239–253). Elmsford, N.Y.: Pergamon Press.Google Scholar
  97. Strauss, B. S., & Silverstein, M. L. (1986). Luria-Nebraska measures in neuropsychologically nonimpaired schizophrenics: A comparison with normal subjects. International Journal of Clinical Neuropsychology, 8, 35–38.Google Scholar
  98. Tal, C. (1988). Intra-and inter-hemispheric dysfunction in schizophrenic and affective disorders. Unpublished doctoral dissertation, Northwestern University.Google Scholar
  99. Taylor, M. A., & Abrams, R. (1984). Cognitive impairment in schizophrenia. American Journal of Psychiatry, 141, 196–201.PubMedGoogle Scholar
  100. Taylor, M. A., & Abrams, R. (1987). Cognitive impairment patterns in schizophrenia and affective disorders. Journal of Neurology, Neurosurgery and Psychiatry, 50, 895–899.CrossRefGoogle Scholar
  101. Taylor, M. A., Greenspan, B., & Abrams, R. (1979). Lateralized neuropsychological dysfunction in affective disorder and schizophrenia. American Journal of Psychiatry, 136, 1031–1034.PubMedGoogle Scholar
  102. Taylor, M. A., Redfield, J., & Abrams, R. (1981). Neuropsychological dysfunction in schizophrenia and affective disease. Biological Psychiatry, 16, 467–478.PubMedGoogle Scholar
  103. Townes, B. D., Martin, D. C., Nelson, D., Prosser, R., Pepping, M., Maxwell, J., Peel, J., & Preston, M. (1985). Neurobehavioral approach to classification of psychiatric patients using a competency model. Journal of Consulting and Clinical Psychology, 53, 33–42.PubMedCrossRefGoogle Scholar
  104. van Kammen, D. P., Mann, L. S., Sternberg, D. E., Scheinen, M., Ninan, P. T, Marder, S. R., van Kammen, W. B., Rieder, R. O., Linnoila, M. (1983). Dopamine-β-hydroxylase activity and homovanillic acid in spinal fluid of schizophrenics with brain atrophy. Science, 220, 974–977.PubMedCrossRefGoogle Scholar
  105. Waddington, J. L. (1985). Structural brain pathology and clinical features in schizophrenia: Further clues on the neurobiology of psychosis? Trends in Neurosciences, 8, 374–375.CrossRefGoogle Scholar
  106. Walker, E. (1988). Cognitive performance profiles and the course of schizophrenia. Unpublished manuscript.Google Scholar
  107. Walker, E., & Lewine, R. J. (1988). The positive/negative symptom distinction in schizophrenia: Validity and etiologic relevance. Schizophrenia Research, 1, 315–328.PubMedCrossRefGoogle Scholar
  108. Walker, E., & Lewine, R. J. (1990). The prediction of adult-onset schizophrenia from childhood home-movies. American Journal of Psychiatry, 147, 1052–1056.PubMedGoogle Scholar
  109. Walker, E., & McGuire, M. (1982). Intra-and interhemispheric information processing in schizophrenia. Psychological Bulletin, 92, 701–715.PubMedCrossRefGoogle Scholar
  110. Walker, E., & Shaye, J. (1982). Familial schizophrenia: A predictor of neuromotor and attentional dysfunction in schizophrenia. Archives of General Psychiatry, 39, 1153–1160.PubMedCrossRefGoogle Scholar
  111. Wegner, J. T., Catalano, F., Gibralter, J., & Kane, J. M. (1985). Schizophrenics with tardive dyskinesianeuropsychological deficit and family psychopathology Archives of General Psychiatry, 42, 860–865.PubMedCrossRefGoogle Scholar
  112. Weinberger, D. R., & Berman, K. F. (1988). Speculation on the meaning of cerebral metabolic hypofrontality in schizophrenia. Schizophrenia Bulletin, 14, 157–168.PubMedCrossRefGoogle Scholar
  113. Weinberger, D. R., Torrey, E. F., & Wyatt, R. J. (1979). Cerebellar atrophy in chronic schizophrenia. Lancet, 1, 718–719.PubMedCrossRefGoogle Scholar
  114. Weinberger, D. R., DeLisi, L. E., Perman, G. R, Targum, S., & Wyatt, R. J. (1982). Computed tomography in schizophreniform disorder and other acute psychiatric disorders. Archives of General Psychiatry, 39, 778–783.PubMedCrossRefGoogle Scholar
  115. Weinberger, D. R., Wagner, R. L., & Wyatt, R. J. (1983). Neuropathological studies of schizophrenia: A selective review. Schizophrenia Bulletin, 9, 193–212.PubMedCrossRefGoogle Scholar
  116. Weinberger, D. R., Berman, K. E, & Zec, R. F., (1986). Physiologic dysfunction of lateral prefrontal cortex in schizophrenia. Archives of General Psychiatry, 43, 114–125.PubMedCrossRefGoogle Scholar
  117. Wexler, B., & Heninger, G. R. (1980). Effects of concurrent administration of verbal and spatial visual tasks on a language related dichotic listening measure of perceptual asymmetry. Neuropsychologia, 18, 379–382.PubMedCrossRefGoogle Scholar
  118. Williams, A. O., Reveley, M. A., Kolakowska, T, Ardern, M., & Mandelbrote, B. M. (1985). Schizophrenia with good and poor outcome II: Cerebral ventricular size and its clinical significance. British Journal of Psychiatry, 146, 239–246.PubMedCrossRefGoogle Scholar
  119. Wooten, A. J. (1983). MMPI profiles among neuropsychology patients. Journal of Clinical Psychology, 39, 392–406.PubMedCrossRefGoogle Scholar
  120. Yates, W. R., Jacoby, C. G., & Andreasen, N. C. (1987). Cerebellar atrophy in schizophrenia and affective disorder. American Journal of Psychiatry, 144, 465–467.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • Elaine Walker
    • 1
  • Marsha Lucas
    • 1
  • Richard Lewine
    • 1
  1. 1.Departments of Psychiatry and PsychologyEmory UniversityAtlantaUSA

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