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Some Perspectives on the Transmission of Giardiasis

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Giardia and Giardiasis

Abstract

A number of aspects of the genus Giardia have been a source of great controversy among parasitologists for decades. Much of the difficulty centers around the taxonomy of this flagellate. This has never been completely resolved; it will be discussed further later in this chapter. Giardia spp. investigations proceeded, at a fairly constant level, until the mid-1960s, when research publications pertaining to this parasite diminished considerably. The work with Giardia was continued, over a period of about a decade, by a small group of dedicated workers, without the benefit of much financial support for their research. One reason for this lack of support has been the belief that this organism is of no public health significance in our society. It was considered, and with considerable justification, to be a rather unusual flagellate of doubtful pathologic significance. Many considered it to be more of an exotic parasite, which on occasion produced a diarrheic syndrome in travelers. The research, of course, did progress, and a considerable amount of significant information was developed in such areas as in vitro cultivation (Meyer, 1976; Fortess and Meyer, 1976) and cellular morphology, using both transmission and scanning electron microscopy (Friend, 1966; Erlandsen, 1974; Erlandsen and Chase, 1974; Sheffield and Bjorvatn, 1977) and immunology, by Roberts-Thomson and his co-workers (1976, 1981), Stevens et al. (1978), Visvesvara and Healy (1980), Visvesvara et al. (1980), and many others.

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References

  • Ansari, M. A. R., 1952, Contribution à l’étude du genre Giardia Kunstler, 1882 (Mastigophora: Octomitidae), Ann. Parasitol. Hum. Comp. 27:421–479.

    PubMed  CAS  Google Scholar 

  • Armaghan, V., 1937, Biological studies on the Giardia of rats, Am. J. Hyg. 26:236–258.

    Google Scholar 

  • Associated Press, 1979, Parasite-ridden beavers pinpointed as source of illness in Pennsylvania, Minneapolis Tribune, Nov. 6, 1979, p. 4B.

    Google Scholar 

  • Aust Kettis, A., and Magnius, L., 1973, Giardia lamblia infection in a group of students after a visit to Leningrad in March, 1970, Scand. J. Infect. Dis. 5:289–292.

    Google Scholar 

  • Barbour, A. G., Nichols, C. R., and Fukushima, T., 1976, An outbreak of giardiasis, Am. J. Trop. Med. Hyg. 25:384–389.

    PubMed  CAS  Google Scholar 

  • Bemrick, W. J., 1962, The host specificity of Giardia from laboratory strains of Mus musculus and Rattus norvegicus, J. Parasitol. 68:287–290.

    Article  Google Scholar 

  • Bemrick, W. J., 1963, Observations on dogs infected with Giardia, J. Parasitol. 49:1031–1032.

    Article  PubMed  CAS  Google Scholar 

  • Bingham, A. K., and Meyer, E. A., 1979, Giardia excystation can be induced in vitro in acidic solution, Nature (London) 277:301–302.

    Article  CAS  Google Scholar 

  • Boeck, W. C, 1917, Mitosis in Giardia microti, Univ. Calif. Publ. Zool. 19:85–134.

    Google Scholar 

  • Brandborg, L. L., Tankersley, L. B., Gottlieb, S., Barancik, S., and Sartor, V. E., 1967, Histological demonstration of mucosal invasion by Giardia lamblia in man, Gastroen-terology 52:143–150.

    CAS  Google Scholar 

  • Brodsky, R. E., Spencer, H. C, Jr., and Schultz, M. G., 1974, Giardiasis in American travelers to the Soviet Union, J. Infect. Dis. 130:319–323.

    Article  PubMed  CAS  Google Scholar 

  • Chakravarti, A., 1968, Giardiasis and its treatment with particular reference to Flagyl therapy, Indian Pract. 21:808–814.

    Google Scholar 

  • Conroy, D. A., 1960, Giardia in Christmas pudding, Rev. Iber. Parasitol. 20:567–571.

    Google Scholar 

  • Craun, G. F., 1979, Waterborne giardiasis in the United States: A review, Am. J. Public Health 69:817–819.

    Article  PubMed  CAS  Google Scholar 

  • Cripps, A., Denny, P. J., Fisher, S., Green, P., and O’Connor, B. F., 1975, A health and social survey of a group of children from rural New South Wales, Med. J. Aust. 2:214–218.

    PubMed  CAS  Google Scholar 

  • Cutting, J. W., 1975, A survey of intestinal parasitism in a community of the Pan American highway route in eastern Panama, Bull. Pan. Am. Health Organ. 9:13–18.

    PubMed  CAS  Google Scholar 

  • Danciger, M., and Lopez, M., 1975, Number of Giardia in the feces of infected children, Am. J. Trop. Med. Hyg. 24:237–242.

    PubMed  CAS  Google Scholar 

  • Davies, R., 1978, Giardiasis: A problem in Colorado, Wildl. Dis. Assoc. Newsl. (January), p. 3.

    Google Scholar 

  • Davies, R. B., and Hibler, C. P., 1979, Animal reservoirs and cross-species transmission of Giardia, in: Waterborne Transmission of Giardiasis (W. Jakubowski and J. C. Hoff, eds.), Environmental Protection Agency 600/9-79-001, pp. 104-126.

    Google Scholar 

  • DeCarneri, I., Trane, F., and Mandelli, V., 1977, Giardia muris: Oral infection with one trophozoite and generation time in mice, Trans. R. Soc. Trop. Med. Hyg. 71:438.

    Article  CAS  Google Scholar 

  • Dritz, S. K., 1980, Medical aspects of homosexuality, N. Engl.J. Med. 302:463–464.

    Article  PubMed  CAS  Google Scholar 

  • Dykes, A. C, Juranek, D. D., Lorenz, R. A., Sinclair, S., Jakubowski, W., and Davis, R., 1980, Municipal waterborne giardiasis: An epidemiologic investigation, Ann. Intern. Med. 92:165–170.

    Article  PubMed  CAS  Google Scholar 

  • Erlandsen, S. L., 1974, Scanning electron microscopy of intestinal giardiasis: Lesions of the microvillous border of villus epithelial cells produced by trophozoites of Giardia, in Scanning Electron Microscopy, 1973 (O. Johari, ed.), pp. 775–782, IIT Research Institute, Chicago.

    Google Scholar 

  • Erlandsen, S. L., and Chase, D. G., 1974, Morphologic alterations in the microvillous border of villous epithelial cells produced by intestinal microorganisms, Am. J. Clin. Nutr. 27:1277–1286.

    PubMed  CAS  Google Scholar 

  • Fantham, H. B., and Porter, A., 1916, The pathogenicity of Giardia (Lamblia) intestinalis to men and to experimental animals, Biol. Med. J. 2:139–141.

    CAS  Google Scholar 

  • Felman, Y. M., and Nikitas, M. A., 1979, Sexually transmitted enteric pathogens in New York City, N.Y. State J. Med. 79:1412–1413.

    PubMed  CAS  Google Scholar 

  • Filice, F. P., 1952, Studies on the cytology and life history of a Giardia from the laboratory rat, Univ. Calif. Publ. Zool. 57:53–143.

    Google Scholar 

  • Fortess, E., and Meyer, E. A., 1976, Isolation and axenic cultivation of Giardia trophozoites from the guinea pig, J. Parasitol. 62:689.

    Article  PubMed  CAS  Google Scholar 

  • Friend, D. S., 1966, The fine structure of Giardia muris, J. Cell Biol. 29:317–332.

    Article  PubMed  CAS  Google Scholar 

  • Frost, F., Plan, B., and Liechty, B., 1980, Giardia prevalence in commercially trapped animals, J. Environ. Health 42:245–249.

    Google Scholar 

  • Geddes, A. M., 1973, Giardiasis in England, Br. Med. J. 4:236.

    Article  PubMed  CAS  Google Scholar 

  • Grant, D. R., and Woo, P. T. K., 1978a, Comparative studies of Giardia spp. in small animals in southern Ontario. I. Prevalence and identity of the parasites with a taxonomic discussion of the genus, Can. J. Zool. 56:1348–1359.

    Article  PubMed  CAS  Google Scholar 

  • Grant, D. R., and Woo, P. T. K., 1978b, Comparative studies on Giardia spp. in small mammals in southern Ontario. II. Host specificity and infectivity of stored cysts, Can. J. Zool. 56:1360–1366.

    Article  PubMed  CAS  Google Scholar 

  • Grant, D. R., and Woo, P. T. K., 1979, Comparative studies on Giardia spp. in small mammals in southern Ontario. III. Duration and cyst production in natural and experimental infections, Can.J. Zool. 57:307–313.

    Article  PubMed  CAS  Google Scholar 

  • Haiba, M. H., 1956, Further study on the susceptibility of murines to human giardiasis, Z. Parasitenkd. 17:339–345.

    Article  PubMed  CAS  Google Scholar 

  • Harinasuta, C., Sornamani, S., Migasena, P., Vivatanasesth, P., Pongpaew, P., Intarakao, L., and Vudhivai, N., 1976, Socioeconomic, health and nutritional status of the villagers in the Hong Wai irrigation area, Khou Kaen, northeast Thailand, Southeast Asian J. Trop. Med. Public Health 7:601–621.

    PubMed  CAS  Google Scholar 

  • Hegner, R. W., 1922, A comparative study of the giardias living in man, rabbit, and dog, Am. J. Hyg. 2:442–454.

    Google Scholar 

  • Hegner, R. W., 1926, The biology of host-parasite relationships among protozoa living in man, Q. Rev. Biol 1:393–418.

    Article  Google Scholar 

  • Hewlett, E. L., Andrews, J. S., Jr., Ruffier, J., and Schaefer, F. W., III, 1982, Experimental infection of mongrel dogs with Giardia lamblia cysts and cultured trophozoites, J. Infect. Dis. 145:89–93.

    Article  PubMed  CAS  Google Scholar 

  • Jokipii, L., and Jokipii, A. M. M., 1974, Giardiasis in travelers: A prospective study, J. Infect. Dis. 130:295–299.

    Article  PubMed  Google Scholar 

  • Karapetyan, A. E., 1960, A method of cultivation of Lamblia, Tsitologiya 2:379–384.

    Google Scholar 

  • Kean, B. H., William D. C, and Luminais, S. K., 1979, Epidemic of amoebiasis and giardiasis in a biased population, Br. J. Verier. Dis. 55:375–378.

    CAS  Google Scholar 

  • Keifer, A., Roberto, R. R., Powers, L., Gaston, J., Sherwood, R. W., Johnston, L., Blair, J., Early, B., Hopkins, R. S., Scott, E., Smede, R., Osterud, H., Slifman, N., Shilke, J., Hills, L., Goodins, J. A., Burkhart, T. J., Jenkins, M. T., Witte, E. J., McCarthy, M., de Melfî, T., Erb, J., and Lippy, E. C, 1980, Waterborne giardiasis in California, Colorado, Oregon, Pennsylvania, Morbid. Mortal. Weekly Rep. 29:127–123.

    Google Scholar 

  • Kirner, J. C, Littler, J. D., and Angelo, L. A., 1978, A waterborne outbreak of giardiasis in Camas, Washington, J. Am. Water Works Assoc. 70:35–40.

    Google Scholar 

  • Klima, M., Gyorkey, M. A., Min, K., and Gyorkey, F., 1977, Electron microscopy in the diagnosis of giardiasis, Arch. Pathol. Lab. Med. 101:133–135.

    PubMed  CAS  Google Scholar 

  • Knight, R., 1980, Epidemiology and transmission of giardiasis, Trans. R. Soc. Trop. Med. Hyg. 74:433–436.

    Article  PubMed  CAS  Google Scholar 

  • Kulda, J., and Nohynkova, E., 1978, Flagellates of the human intestine and of intestines of other species, in: Protozoa of Veterinary and Medical Interest (J.P. Kreier, ed.), 2:1–138, Academic Press, New York.

    Google Scholar 

  • Lavier, G., 1924, Deux especes de Giardia du rat d’egout Parisien (Epimys norvegicus), Ann. Parasitol. Hum. Comp. 11:161–168.

    Google Scholar 

  • Lippy, E. C, 1978, Tracing a giardiasis outbreak at Berlin, New Hampshire, J. Am. Water Works Assoc. 70:512–520.

    Google Scholar 

  • Mastrandrea, G., and Micarelli, A., 1968, Search for parasites in vegetables from the local markets in the city of Rome, Arch. Ital. Sci. Med. Trop. Parassitol. 49:55–59.

    PubMed  CAS  Google Scholar 

  • Meyer, E. A., 1976, Giardia lamblia: Isolation and axenic cultivation, Exp. Parasitol. 39:101–105.

    Article  PubMed  CAS  Google Scholar 

  • Meyer, E. A., and Jarroll, E. L., 1980, Giardiasis, Am. J. Epidemiol 111:1–12.

    PubMed  CAS  Google Scholar 

  • Meyers, J. D., Kuharic, H. A., and Holmes, K. K., 1977, Giardia lamblia infection in homosexual men, Br. J. Vener. Dis. 53:54–55.

    PubMed  CAS  Google Scholar 

  • Morecki, R., and Parker, J. G., 1967, Ultrastructural studies of the human Giardia lamblia and subjacent jejunal mucosa in a subject with steatorrhea, Gastroenterology 52:151–164.

    PubMed  CAS  Google Scholar 

  • Most, H., 1968, Manhattan: A “tropic isle”?, Am. J. Trop. Med. Hyg. 17:333–354.

    PubMed  CAS  Google Scholar 

  • Naiman, H. L., Sekla, L., and Albritton, W. L., 1980, Giardiasis and other intestinal parasitic infections in a Manitoba residential school for the mentally retarded Can. Med. Assoc. J. 122:185–188.

    PubMed  CAS  Google Scholar 

  • Nalin, D. R., Rhead, J., Rennels, M., O’Donnell, S., Levine, M. M., Bergquist, E., Hughes, T., and Hormick, R. B., 1978, Cannabis, hypochlorhydria and cholera, Lancet 2:859–862.

    Article  PubMed  CAS  Google Scholar 

  • Nemanic, P., Owen, R. L., Stevens, D. P., and Mueller, J. S., 1979, Ultrastructural observations on giardiasis in a murine model. II. Endosymbiosis and organelle distribution in Giardia muris and comparison with Giardia lamblia, J. Infect. Dis. 110:222–228.

    Article  Google Scholar 

  • Nieschulz, O., 1924, Über den Bau von Giardia caprae Mihi, Arch. Protistenkd. 49:278–286.

    Google Scholar 

  • Osterholm, M. T., Forfang, J. C, Ristenen, T. L., Dean, A. G., Washburn, J. W., Godes, J. R., Rude, R. A., and McCullough, J. G., 1981, An outbreak of foodborne giardiasis, N. Engl. J. Med. 304:24–28.

    Article  PubMed  CAS  Google Scholar 

  • Padchenko, J. K., and Stolyarchuk, N. G., 1970, Dogs as a spontaneous carrier of Lamblia and probable source and vector lambliosis in nature, Vestn. Zool. 4:56–61.

    CAS  Google Scholar 

  • Rendtorff, R. C, 1954, The experimental transmission of human intestinal parasites. II: Giardia lamblia cysts given in capsules, Am. J. Hyg. 59:209–220.

    PubMed  CAS  Google Scholar 

  • Rendtorff, R. C, 1975, Giardia in water, Ann. Intern. Med. 82:280–281.

    Article  PubMed  CAS  Google Scholar 

  • Ridley, M. J., and Ridley, D. S., 1976, Serum antibodies and jejunal histology in giardiasis associated with malabsorption, J. Clin. Pathol. 29:30–34.

    Article  PubMed  CAS  Google Scholar 

  • Roberts-Thomson, I. C, and Anders, R. F., 1981, Serum antibodies in adults with giardiasis, Gastroenterology 80:1262.

    Google Scholar 

  • Roberts-Thomson, I. C, Stevens, D. P., Mahmoud, A. A. F., and Warren, K. S., 1976, Giardiasis in the mouse: An animal model, Gastroenterology 71:57–61.

    PubMed  CAS  Google Scholar 

  • Saha, T. K., and Ghosh, T. K., 1977, Invasion of the small intestinal mucosa by Giardia lamblia in man, Gastroenterology 72:402–405.

    PubMed  CAS  Google Scholar 

  • Sebesteny, A., 1974, The transmission of intestinal flagellates in mice, Lab. Anim. 3:71–77.

    Article  Google Scholar 

  • Sehgal, A. K., Grewal, M. S., Chakravarti, R. N., Broor, S. L., Deka, N. C, and Chhuttani, P. N., 1976, Experimental giardiasis in albino rats, Indian J. Med. Res. 64:1015–1018.

    PubMed  CAS  Google Scholar 

  • Shaw, P. K., Brodsky, R. E., Lyman, D. O., Wood, B. T., Hibler, C. P., Healy, G. R., MacLeod, K. I. E., Stahy, W., and Schultz, M. G., 1977, A community-wide outbreak of giardiasis with evidence of transmission by a municipal water supply, Ann. Intern. Med. 87:426–432.

    Article  PubMed  CAS  Google Scholar 

  • Sheffield, H. G., and Bjorvatn, B., 1977, Ultrastructure of the cyst of Giardia lamblia, Am. J. Trop. Med. Hyg. 26:23–30.

    PubMed  CAS  Google Scholar 

  • Shelton, G. C., 1954, Giardiasis in the chinchilla. I. Observations on morphology, location in the intestinal tract and host specificity, Am. J. Vet. Res. 15:71–74.

    PubMed  CAS  Google Scholar 

  • Simon, C. E., 1922, A critique of the supposed rodent origin of human giardiasis, Am. J. Hyg. 1:406–434.

    Google Scholar 

  • Smith, P. D., Gillin, F. D., Brown, W. R., and Nash, T. E., 1981, IgG antibody to Giardia lamblia detected by enzyme-linked immunosorbent assay, Gastroenterology 80:1476–1480.

    PubMed  CAS  Google Scholar 

  • Stevens, D. P., Frank, D. M., and Mahmoud, A. A. F., 1978, Thymus dependency of host resistance to Giardia muris infection: Studies in nude mice, J. Immunol. 120:680–682.

    PubMed  CAS  Google Scholar 

  • Veazie, L., 1969, Epidemic giardiasis, N. Engl. J. Med. 281:853.

    PubMed  CAS  Google Scholar 

  • Visvesvara, G. S., and Healy, G. R., 1980, The possible use of an indirect immunoflu-orescent test using axenically grown Giardia lamblia antigens in diagnosing giardiasis, in: Waterborne Transmission of Giardiasis (W. Jakubowski and J. C. Hoff, eds.), Environmental Protection Agency, 600/9-79-001, pp. 53-63.

    Google Scholar 

  • Visvesvara, G. S., Smith, P. D., Healy, G. R., and Brown, W. R., 1980, An immunofluo-rescence test to detect serum antibodies to Giardia lamblia, Ann. Intern. Med. 93:802–805.

    Article  PubMed  CAS  Google Scholar 

  • Walzer, P. D., Wolfe, M. S., and Schultz, M. G., 1971, Giardiasis in travelers, J. Infect. Dis. 124:235–237.

    Article  PubMed  CAS  Google Scholar 

  • Wenrich, D. H., 1940, Observations on parasites and inclusion bodies in certain intestinal protozoa, Science 92:416–417.

    Google Scholar 

  • Zisman, M., 1977, Blood group A and giardiasis, Lancet 2:1285.

    Article  PubMed  CAS  Google Scholar 

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Bemrick, W.J. (1984). Some Perspectives on the Transmission of Giardiasis. In: Erlandsen, S.L., Meyer, E.A. (eds) Giardia and Giardiasis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0594-9_22

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